Pacek Lauren R, Cioe Patricia A
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, 27707, USA.
Behavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, 21224, USA.
Curr HIV/AIDS Rep. 2015 Dec;12(4):413-20. doi: 10.1007/s11904-015-0281-9.
Cigarette smoking remains highly prevalent among persons living with human immunodeficiency virus (HIV), estimated to be 40-75 %, and is significantly higher than what is observed among the general population. Health risks of smoking in this population include cardiovascular disease; bacterial pneumonia, chronic obstructive pulmonary disease, and other respiratory conditions; lung cancer and other malignancies; adverse cognitive and neurological outcomes; low birth weight, preterm birth, and small-for-gestational-age infants; and overall mortality. Smokers with HIV now lose more life years to smoking than they do to the HIV itself. A majority of smokers living with HIV report being interested in cessation, and a significant proportion has made recent quit attempts. There is a general paucity of large, randomized controlled trials of smoking cessation interventions among smokers living with HIV, and among the existing research, cessation rates are suboptimal. Greater resources and effort should be allocated to developing and evaluating cessation treatment modalities for smokers living with HIV. Efforts to individualize and tailor treatments to address specific client needs and comorbidities are warranted. HIV care providers and other health professionals can play a key role in improving health among this population by regularly screening for smoking and promoting cessation.
吸烟在人类免疫缺陷病毒(HIV)感染者中仍然非常普遍,估计比例为40%-75%,显著高于普通人群中的吸烟比例。该人群吸烟的健康风险包括心血管疾病;细菌性肺炎、慢性阻塞性肺疾病和其他呼吸道疾病;肺癌和其他恶性肿瘤;不良认知和神经学后果;低出生体重、早产和小于胎龄儿;以及全因死亡率。感染HIV的吸烟者因吸烟失去的生命年数现在比因HIV本身失去的更多。大多数感染HIV的吸烟者表示有戒烟意愿,并且有相当比例的人最近尝试过戒烟。在感染HIV的吸烟者中,关于戒烟干预措施的大型随机对照试验普遍较少,在现有研究中,戒烟率并不理想。应该投入更多资源和精力来开发和评估针对感染HIV的吸烟者的戒烟治疗方法。有必要努力使治疗个性化并进行调整,以满足特定客户的需求和合并症。HIV护理提供者和其他卫生专业人员可以通过定期筛查吸烟情况并促进戒烟,在改善该人群的健康方面发挥关键作用。