Bowker Katharine, Campbell Katarzyna A, Coleman Tim, Lewis Sarah, Naughton Felix, Cooper Sue
Division of Primary Care, University of Nottingham, Nottingham, United Kingdom;
Division of Epidemiology and Public Health, Nottingham City Hospital, Nottingham, United Kingdom;
Nicotine Tob Res. 2016 May;18(5):906-12. doi: 10.1093/ntr/ntv205. Epub 2015 Sep 21.
Pregnant smokers may be offered nicotine replacement therapy (NRT) alongside behavioral support to assist with a quit attempt. Yet trials of NRT have found adherence to be low among pregnant women, and this has made it difficult to determine the efficacy of NRT. The aim of this study is to understand the experience of pregnant women who use NRT but discontinue this early or do not use the medication as recommended.
Semi-structured telephone interviews were conducted with 14 pregnant smokers who had recently been prescribed NRT, but self-reported poor NRT adherence or discontinuing treatment prematurely. Data were transcribed and analyzed using inductive thematic analysis
There were four main themes identified; expectations of NRT, experience of using NRT, safety concerns and experience of using e-cigarettes. Some women intentionally used NRT to substitute a proportion of their cigarette intake and smoked alongside. Most women smoked while using NRT. Women who underutilized NRT did so as they experienced side effects, or were concerned that using NRT instead of smoking could actually increase their nicotine exposure and potential for increased nicotine dependence or fetal harm. Most women spoke about the use of e-cigarettes as a smoking cessation method but only a few had actually experienced using them during pregnancy.
Many women underused NRT but simultaneously smoked. Challenging negative perceptions about NRT and educating women further about the risks of smoking may encourage them to use NRT products as recommended.
These findings add to the research surrounding the efficacy of NRT during pregnancy by providing insight into how pregnant women use NRT during a quit attempt and how this may influence adherence. It may assist health professionals to support pregnant smokers by increasing their understanding about the differing ways in which women use NRT and help them address concerns women may have about the safety of NRT.
对于怀孕的吸烟者,可在提供行为支持的同时给予尼古丁替代疗法(NRT),以帮助其尝试戒烟。然而,NRT试验发现孕妇对该疗法的依从性较低,这使得确定NRT的疗效变得困难。本研究的目的是了解使用NRT但过早停药或未按推荐使用该药物的孕妇的经历。
对14名近期开具了NRT处方,但自我报告NRT依从性差或过早停药的怀孕吸烟者进行了半结构化电话访谈。使用归纳主题分析法对数据进行转录和分析。
确定了四个主要主题;对NRT的期望、使用NRT的经历、安全担忧以及使用电子烟的经历。一些女性有意使用NRT来替代一部分香烟摄入量,并同时吸烟。大多数女性在使用NRT时仍吸烟。未充分使用NRT的女性是因为她们经历了副作用,或者担心使用NRT而非吸烟实际上会增加她们的尼古丁摄入量以及增加尼古丁依赖或对胎儿造成伤害的可能性。大多数女性谈到将使用电子烟作为戒烟方法,但只有少数人在怀孕期间实际使用过电子烟。
许多女性未充分使用NRT,但同时仍在吸烟。挑战对NRT的负面看法并进一步教育女性了解吸烟的风险,可能会鼓励她们按推荐使用NRT产品。
这些发现通过深入了解孕妇在尝试戒烟期间如何使用NRT以及这可能如何影响依从性,为围绕孕期NRT疗效的研究增添了内容。这可能有助于健康专业人员支持怀孕吸烟者,方法是增加他们对女性使用NRT的不同方式的理解,并帮助他们解决女性可能对NRT安全性存在的担忧。