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将生物统计学生长曲线模型应用于认知发展中的发育同步性:路易斯维尔双生子研究

Applying Biometric Growth Curve Models to Developmental Synchronies in Cognitive Development: The Louisville Twin Study.

作者信息

Finkel Deborah, Davis Deborah Winders, Turkheimer Eric, Dickens William T

机构信息

Department of Psychology, Indiana University Southeast, 4201 Grant Line Road, New Albany, IN, USA.

Department of Pediatrics, University of Louisville, Louisville, KY, USA.

出版信息

Behav Genet. 2015 Nov;45(6):600-9. doi: 10.1007/s10519-015-9747-1. Epub 2015 Sep 21.

Abstract

Biometric latent growth curve models were applied to data from the LTS in order to replicate and extend Wilson's (Child Dev 54:298-316, 1983) findings. Assessments of cognitive development were available from 8 measurement occasions covering the period 4-15 years for 1032 individuals. Latent growth curve models were fit to percent correct for 7 subscales: information, similarities, arithmetic, vocabulary, comprehension, picture completion, and block design. Models were fit separately to WPPSI (ages 4-6 years) and WISC-R (ages 7-15). Results indicated the expected increases in heritability in younger childhood, and plateaus in heritability as children reached age 10 years. Heritability of change, per se (slope estimates), varied dramatically across domains. Significant genetic influences on slope parameters that were independent of initial levels of performance were found for only information and picture completion subscales. Thus evidence for both genetic continuity and genetic innovation in the development of cognitive abilities in childhood were found.

摘要

生物特征潜在增长曲线模型被应用于来自长期追踪研究(LTS)的数据,以复制和扩展威尔逊(《儿童发展》54:298 - 316, 1983)的研究结果。对1032名个体在4至15岁期间的8个测量时点进行了认知发展评估。潜在增长曲线模型适用于7个分量表的正确百分比:信息、相似性、算术、词汇、理解、图片完成和积木设计。模型分别适用于韦氏幼儿智力量表(WPPSI,4至6岁)和韦氏儿童智力量表修订版(WISC - R,7至15岁)。结果表明,在幼儿期遗传力预期会增加,而当儿童达到10岁时遗传力会趋于平稳。变化本身的遗传力(斜率估计)在不同领域差异很大。仅在信息和图片完成分量表中发现了与初始表现水平无关的对斜率参数的显著遗传影响。因此,在儿童认知能力发展中发现了遗传连续性和遗传创新的证据。

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