巴西人群中孕11至14⁺²周胎儿颅内透明层测量的参考范围。
Reference range for the fetal intracranial translucency measurement between 11 and 14 + 2 weeks of gestation in a Brazilian population.
作者信息
Peixoto Alberto Borges, Caldas Taciana Mara, Lasmar Larrisa Abu, Martins Wellington P, Pares David Baptista, Araujo Júnior Edward
机构信息
a Mario Palmério University Hospital, University of Uberaba (UNIUBE) , Uberaba , MG , Brazil .
b Radiologic Clinic of Uberaba (CRU) , Uberaba , MG , Brazil .
出版信息
J Matern Fetal Neonatal Med. 2016;29(16):2588-91. doi: 10.3109/14767058.2015.1099155. Epub 2015 Oct 20.
OBJECTIVE
To establish a reference range for the fetal intracranial translucency (IT) measurement between 11 and 14 + 2 weeks in a Brazilian population.
METHODS
A retrospective cross-sectional study was performed with 199 low-risk singleton pregnancies during the first trimester ultrasound exam. The IT (fourth ventricle width) measurement was performed in a mid-sagittal view of fetal profile defined by two echogenic borders - the dorsal part of the brain stem anteriorly and the choroid plexus of the fourth ventricle posteriorly. Polynomial regression was used to obtain the best fit using fetal IT measurements and crown-rump length (CRL). Percentiles 5th, 50th and 95th were determined for each gestational age.
RESULTS
The mean of fetal IT ranged from 1.6 mm at CRL 45 to 2.0 mm at CRL 84 mm. A best fit curve was a first-degree polynomial regression: IT measurement = 1.001 + 0.0124 × CRL (R(2)=0.09).
CONCLUSION
Reference range for the fetal IT measurement between 11 and 14 + 2 weeks of gestation in a Brazilian population was established.
目的
在巴西人群中建立孕11周到14⁺²周胎儿颅内透明层（IT）测量的参考范围。
方法
对199例低风险单胎妊娠进行回顾性横断面研究，于孕早期超声检查时进行。IT（第四脑室宽度）测量在胎儿侧位正中矢状面上进行，该平面由两个强回声边界界定——前方为脑干背侧部分，后方为第四脑室脉络丛。采用多项式回归，利用胎儿IT测量值和头臀长（CRL）获得最佳拟合。确定每个孕周的第5、50和95百分位数。
结果
胎儿IT平均值在CRL为45时为1.6毫米，在CRL为84毫米时为2.0毫米。最佳拟合曲线为一次多项式回归：IT测量值 = 1.001 + 0.0124 × CRL（R² = 0.09）。
结论
建立了巴西人群孕11周到14⁺²周胎儿IT测量的参考范围。
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