对比剂相关急性肾损伤

Contrast-associated Acute Kidney Injury.

作者信息

Weisbord Steven D, Palevsky Paul M

机构信息

Renal Section, VA Pittsburgh Healthcare System, Room 7E120 (111F-U), University Drive, Pittsburgh, PA 15240, USA; Renal-Electrolyte Division, University of Pittsburgh School of Medicine, A919 Scaife Hall, 3550 Terrace Street, Pittsburgh, PA 15261, USA.

Renal-Electrolyte Division, University of Pittsburgh School of Medicine, A919 Scaife Hall, 3550 Terrace Street, Pittsburgh, PA 15261, USA; Renal Section, VA Pittsburgh Healthcare System, Room 7E123 (111F-U), University Drive, Pittsburgh, PA 15240, USA.

出版信息

Crit Care Clin. 2015 Oct;31(4):725-35. doi: 10.1016/j.ccc.2015.06.008. Epub 2015 Jul 29.

DOI:10.1016/j.ccc.2015.06.008

PMID:26410140

Abstract

Contrast-associated acute kidney injury (CAAKI) is a common iatrogenic condition. The principal risk factors for CAAKI are underlying renal impairment; diabetes in the setting of kidney disease; and intravascular volume depletion, effective or absolute. CAAKI is associated with serious adverse short-term and long-term outcomes, including mortality and more rapidly progressive chronic kidney disease, although the causal nature of these associations remains unproved. Patients with chronic kidney disease and other risk factors for CAAKI who present with acute coronary syndrome should undergo indicated angiographic procedures.

摘要

对比剂相关急性肾损伤（CAAKI）是一种常见的医源性疾病。CAAKI的主要危险因素包括潜在的肾功能损害；肾病背景下的糖尿病；以及有效或绝对的血管内容量耗竭。CAAKI与严重的短期和长期不良后果相关，包括死亡率和进展更快的慢性肾病，尽管这些关联的因果性质尚未得到证实。患有慢性肾病和其他CAAKI危险因素且出现急性冠状动脉综合征的患者应接受必要的血管造影检查。