[重度葡萄膜炎的医学治疗]

[Medical treatment of severe uveitis].

作者信息

Berche M, Najjar G, Renard Y, Darwiche A, Musitelli E

出版信息

Ophtalmologie. 1989 Jan-Mar;3(1):37-9.

Abstract

135 patients with chronic uveitis were observed and 23 had therapeutic problems by their severity. The corticoid treatment method, always used in a first time, is studied. When there is corticoresistance, corticodependance or absolute contra-indications, the immunosuppressive drugs are used with reduced doses to avoid an AIDS. The corticoid bolus, the plasma exchange and colchicine are adjuvant treatments. Cyclosporin A brings large hopes but its use is now limited by necessity and serious side effects. Serious uveitis does not answer to a unique therapeutic protocol. The treatment must be adaptable and surgery decided in time.

摘要

对135例慢性葡萄膜炎患者进行了观察，其中23例因病情严重存在治疗问题。研究了首次始终采用的皮质类固醇治疗方法。当出现皮质类固醇抵抗、皮质类固醇依赖或绝对禁忌证时，使用免疫抑制药物并减少剂量以避免艾滋病。皮质类固醇大剂量冲击疗法、血浆置换和秋水仙碱是辅助治疗方法。环孢素A带来了很大希望，但目前其使用因必要性和严重副作用而受到限制。严重葡萄膜炎没有单一的治疗方案。治疗必须具有适应性，并及时决定是否进行手术。