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住院老年患者抗血小板药物的使用

The use of antiplatelet medication in hospitalised elderly patients.

作者信息

Wawruch M, Slezakova V, Murin J, Kuzelova M, Dukat A, Zabka M, Leitmann T, Tisonova J, Kallay Z

出版信息

Bratisl Lek Listy. 2015;116(9):533-8. doi: 10.4149/bll_2015_102.

Abstract

BACKGROUND

The use of antiplatelet agents is strongly recommended for the secondary prevention of ischemic events such as myocardial infarction, stroke/transient ischemic attack (TIA).

OBJECTIVES

The aim of our study was to analyse the use of antiplatelet medication in patients after myocardial infarction, stroke/TIA, and patients with both conditions and to identify patient-related characteristics, which determine the use of such drugs in elderly patients.

METHODS

Study sample (n=372) was derived from 2,157 patients admitted to long-term care departments of three municipal hospitals. The study included patients aged ≥65 years after myocardial infarction, stroke/TIA or both.

RESULTS

Antiplatelet medications were prescribed in 54.8 % and 68.5 % of patients at hospital admission and discharge, respectively. Hospitalisation led to a significant increase in the use of antiplatelet medication in patients after myocardial infarction and in those with the combination of both events. However, in patients after only stroke/TIA, we did not find any significant difference comparing the use of antiplatelet medication at the time of hospital admission and discharge, respectively.

CONCLUSION

Our study revealed that physicians are more aware of the benefits of antiplatelet medication in elderly patients after myocardial infarction or those after both myocardial infarction and stroke/TIA in comparison with patients after only stroke/TIA (Tab. 3, Ref. 32).

摘要

背景

强烈推荐使用抗血小板药物来二级预防缺血性事件,如心肌梗死、中风/短暂性脑缺血发作(TIA)。

目的

我们研究的目的是分析心肌梗死、中风/TIA患者以及同时患有这两种疾病的患者中抗血小板药物的使用情况,并确定决定老年患者使用此类药物的患者相关特征。

方法

研究样本(n = 372)来自三家市立医院长期护理科室收治的2157名患者。该研究纳入了心肌梗死、中风/TIA或两者兼有的≥65岁患者。

结果

入院时和出院时分别有54.8%和68.5%的患者开具了抗血小板药物。住院导致心肌梗死患者以及同时患有这两种疾病的患者中抗血小板药物的使用显著增加。然而,在仅中风/TIA患者中,入院时和出院时抗血小板药物的使用情况比较未发现任何显著差异。

结论

我们的研究表明,与仅中风/TIA患者相比,医生更了解抗血小板药物对心肌梗死后老年患者或心肌梗死和中风/TIA后患者的益处(表3,参考文献32)。

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