种植体支持的单冠、固定局部义齿和种植体支持的牙齿修复体失败率与生存率的Meta分析

Meta-analysis of Failure and Survival Rate of Implant-supported Single Crowns, Fixed Partial Denture, and Implant Tooth-supported Prostheses.

作者信息

Muddugangadhar B C, Amarnath G S, Sonika Radhika, Chheda Pratik S, Garg Ashu

机构信息

Reader, Department of Prosthodontics including Crown and Bridge and Implantology, M R Ambedkar Dental College and Hospital, Bengaluru, Karnataka, India.

Professor and Head, Department of Prosthodontics including Crown and Bridge and Implantology, M R Ambedkar Dental College and Hospital, Bengaluru, Karnataka, India.

出版信息

J Int Oral Health. 2015 Sep;7(9):11-7.

BACKGROUND

Dental implants have become the most viable option for rehabilitation. Although, many studies report the success of these reconstructions using implants, a cumulative data about the various studies and the failure rate still remain unaddressed. Therefore, the purpose of this systematic review was to analyze these data and to derive the cumulative survival rate of different implant-supported prosthesis.

MATERIALS AND METHODS

Manual searches followed by a MEDLINE search were conducted to select prospective and retrospective cohort studies on single crowns (SCs), fixed partial denture (FPD), and tooth implant connected prostheses with a mean follow-up time of minimum of 5 years. Random-effects Poisson's regression models have been used to obtain summary estimates for implant failure and survival rates.

RESULTS

Data were extracted from the final selected 63 studies. In a meta-analysis of these studies, the survival rate of SCs supported by implants (95% CI) was 96.363%, for FPDs was 94.525% and implant tooth-supported prostheses was 91.27% after 5 years of function. The cumulative failure rate per 100 FPD years of the SCs, FPDs, and implant tooth-supported prostheses were 0.684, 0.881, and 1.514, respectively.

CONCLUSION

The study concludes high survival rates for implant-supported SCs followed by implant-supported FPDs can be expected over an observation period of 5 years. However, tooth implant-supported prostheses can be provided if there are certain limitations prohibiting the completely implant-supported prostheses.

背景

牙种植体已成为修复的最可行选择。尽管许多研究报告了使用种植体进行这些修复的成功案例，但关于各项研究及失败率的累积数据仍未得到解决。因此，本系统评价的目的是分析这些数据，并得出不同种植体支持修复体的累积生存率。

材料与方法

先进行人工检索，随后进行MEDLINE检索，以选择关于单冠（SCs）、固定局部义齿（FPD）和牙种植体连接修复体的前瞻性和回顾性队列研究，平均随访时间至少为5年。采用随机效应泊松回归模型来获得种植体失败率和生存率的汇总估计值。

结果

从最终选定的63项研究中提取数据。在对这些研究的荟萃分析中，种植体支持的SCs在功能5年后的生存率（95%CI）为96.363%，FPDs为94.525%，牙种植体支持的修复体为91.27%。SCs、FPDs和牙种植体支持的修复体每100个FPD年的累积失败率分别为0.684、0.881和1.514。