Cresci Gail A, Bawden Emmy
Department of Gastroenterology/Hepatology, Cleveland Clinic, Cleveland, Ohio
Center for Human Nutrition, Cleveland Clinic, Cleveland, Ohio.
Nutr Clin Pract. 2015 Dec;30(6):734-46. doi: 10.1177/0884533615609899. Epub 2015 Oct 8.
Within the last decade, research regarding the human gut microbiome has exploded. While the gastrointestinal tract was once regarded simply as a digestive organ, new technologies have led the science world to wonder about the impact that the gut microbiota may have on human health and disease. The gut microbiome is now becoming known for its role in metabolism, immune defense, and behavior. From in utero variations to those that rapidly occur post partum, our gut microbiome changes with age, environment, stress, diet, and health status as well as medication exposure. This article reviews what is currently known regarding various influences on the gut microbiome and is meant to encourage the reader to further explore the unknown.
在过去十年里,关于人类肠道微生物群的研究呈爆发式增长。虽然胃肠道曾一度仅被视为一个消化器官,但新技术让科学界开始思考肠道微生物群可能对人类健康和疾病产生的影响。如今,肠道微生物群因其在新陈代谢、免疫防御和行为方面的作用而为人所知。从子宫内的变化到产后迅速发生的变化,我们的肠道微生物群会随着年龄、环境、压力、饮食、健康状况以及药物接触情况而改变。本文综述了目前已知的关于对肠道微生物群的各种影响,旨在鼓励读者进一步探索未知领域。