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TLR activation and ionizing radiation induce strong immune responses against multiple tumor entities.
Oncoimmunology. 2015 May 7;4(11):e1042201. doi: 10.1080/2162402X.2015.1042201. eCollection 2015 Nov.
3
Reprogramming of TLR7 signaling enhances antitumor NK and cytotoxic T cell responses.
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CD4 T Cell and NK Cell Interplay Key to Regression of MHC Class I Tumors upon TLR7/8 Agonist Therapy.
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Cancer immunotherapeutic potential of novel small molecule TLR7 and TLR8 agonists.
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Clinically feasible approaches to potentiating cancer cell-based immunotherapies.
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Systemic cancer therapy with a small molecule agonist of toll-like receptor 7 can be improved by circumventing TLR tolerance.
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Radiation therapy and Toll-like receptor signaling: implications for the treatment of cancer.
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The innate defenders: a review of natural killer cell immunotherapies in cancer.
Front Immunol. 2024 Dec 23;15:1482807. doi: 10.3389/fimmu.2024.1482807. eCollection 2024.
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The Role of Toll-like Receptor Agonists and Their Nanomedicines for Tumor Immunotherapy.
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The expression profile of RNA sensors in colorectal cancer and its correlation with cancer stages.
Transl Cancer Res. 2019 Aug;8(4):1351-1363. doi: 10.21037/tcr.2019.07.45.
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Inflammation and tumor progression: signaling pathways and targeted intervention.
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Differential Effects of Trp53 Alterations in Murine Colorectal Cancer.
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Review of the Efficacy and Mechanisms of Traditional Chinese Medicines as a Therapeutic Option for Ionizing Radiation Induced Damage.
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Tumor-Associated Macrophages in Pancreatic Ductal Adenocarcinoma: Origin, Polarization, Function, and Reprogramming.
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The age-dependent effect of high-dose X-ray radiation on NFκB signaling, structure, and mechanical behavior of the intervertebral disc.
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Trial Watch: Anticancer radioimmunotherapy.
Oncoimmunology. 2013 Sep 1;2(9):e25595. doi: 10.4161/onci.25595. Epub 2013 Jul 3.
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Low-dose irradiation programs macrophage differentiation to an iNOS⁺/M1 phenotype that orchestrates effective T cell immunotherapy.
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Abscopal but desirable: The contribution of immune responses to the efficacy of radiotherapy.
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Antiviral applications of Toll-like receptor agonists.
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Taking dendritic cells into medicine.
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In situ photoimmunotherapy: a tumour-directed treatment for melanoma.
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