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肋骨骨折后的硬膜外镇痛

Epidural Analgesia after Rib Fractures.

作者信息

Zaw Andrea A, Murry Jason, Hoang David, Chen Kevin, Louy Charles, Bloom Matthew B, Melo Nicolas, Alban Rodrigo F, Margulies Daniel R, Ley Eric J

机构信息

Division of Trauma and Critical Care, Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, California, USA.

出版信息

Am Surg. 2015 Oct;81(10):950-4.

Abstract

Pain associated with rib fractures impairs respiratory function and increases pulmonary morbidity. The purpose of this study was to determine how epidural catheters alter mortality and complications in trauma patients. We performed a retrospective study involving adult blunt trauma patients with moderate-to-severe injuries from January 1, 2004 to December 31, 2013. During the 10-year period, 526 patients met the inclusion criteria; 43/526 (8%) patients had a catheter placed. Mean age of patients with epidural catheter (CATH) was higher compared with patients without epidural catheter (NOCATH) (54 vs 48 years, P = 0.021), Injury Severity Score was similar (26 CATH vs 27 NOCATH, P = 0.84), and CATH had higher mean rib fractures (7.4 vs 4.1, P < 0.001). Mortality was lower in CATH (0% vs 13%, P = 0.006). Deep vein thrombosis (DVT) rate was higher in CATH (12% vs. 5%, P = 0.036). After regression analysis, we found catheter placement to be a predictor for DVT (adjusted odds ratios 2.80, P = 0.036). Our center noted increased use of epidural catheters in patients who present with moderate-to-severe injuries. Patients with catheters were older and had a mean of 7.4 ribs fractured. The epidural cohort had longer hospital LOS and decreased mortality. In contrast to other studies, DVT rates were increased in patients who received epidural catheters.

摘要

肋骨骨折相关疼痛会损害呼吸功能并增加肺部发病率。本研究的目的是确定硬膜外导管如何改变创伤患者的死亡率和并发症。我们进行了一项回顾性研究,纳入了2004年1月1日至2013年12月31日期间中度至重度钝性创伤的成年患者。在这10年期间,526例患者符合纳入标准;43/526(8%)例患者放置了导管。与未放置硬膜外导管的患者(NOCATH)相比,放置硬膜外导管的患者(CATH)平均年龄更高(54岁对48岁,P = 0.021),损伤严重程度评分相似(CATH组26分对NOCATH组27分,P = 0.84),且CATH组平均肋骨骨折数更多(7.4根对4.1根,P < 0.001)。CATH组的死亡率较低(0%对13%,P = 0.006)。CATH组深静脉血栓形成(DVT)发生率更高(12%对5%,P = 0.036)。回归分析后,我们发现放置导管是DVT的一个预测因素(调整后的优势比为2.80,P = 0.036)。我们中心注意到中度至重度损伤患者中硬膜外导管的使用增加。放置导管的患者年龄更大,平均肋骨骨折数为7.4根。硬膜外导管组住院时间更长,死亡率降低。与其他研究不同的是,接受硬膜外导管的患者DVT发生率增加。

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