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猪食用木薯引发的肝坏死和变性肌病

Hepatic Necrosis and Degenerative Myopathy Associated with Cassava Feeding in Pigs.

作者信息

Daniel-Igwe Gloria

机构信息

Department of Veterinary Pathology, College of Veterinary Medicine, Michael Okpara University of Agriculture, Umudike PMB 7267, Abia State, Nigeria.

出版信息

J Vet Med. 2014;2014:584945. doi: 10.1155/2014/584945. Epub 2014 Aug 12.

DOI:10.1155/2014/584945
PMID:26464937
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4590868/
Abstract

Forty-three deaths were recorded among pigs fed boiled cassava meal at a private piggery over a period of two years. There were signs of sudden death in some cases with blood exuding from the external nares, vomiting, muscular weakness and pain or reluctance to move, emaciation, and stunted growth. The necropsy lesions included skeletal and cardiac muscle degeneration and necrosis, icterus, hepatic necrosis, and oedema of the dependent parts. The deaths and clinical signs are thought to be due to a non cyanide toxic principle in cassava, possibly the coumarins (scopoletin), which is found in high levels in cassava diet even after heat treatment. Therefore, the use of proper processing technology to obtain cassava products of high quality is recommended.

摘要

在两年时间里,一家私人养猪场中喂食煮木薯粉的猪有43头死亡。部分病例有猝死迹象,包括鼻孔流血、呕吐、肌肉无力与疼痛或不愿活动、消瘦以及生长发育迟缓。尸检病变包括骨骼肌和心肌变性与坏死、黄疸、肝坏死以及下垂部位水肿。这些死亡和临床症状被认为是由于木薯中一种非氰化物毒性成分所致,可能是香豆素(东莨菪亭),即便经过热处理,木薯日粮中该成分含量仍很高。因此,建议采用适当加工技术来获取高质量木薯产品。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68c1/4590868/8c18ae86c6b8/JVM2014-584945.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68c1/4590868/0726c7e2c4ec/JVM2014-584945.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68c1/4590868/f49d66bb9e61/JVM2014-584945.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68c1/4590868/8c18ae86c6b8/JVM2014-584945.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68c1/4590868/0726c7e2c4ec/JVM2014-584945.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68c1/4590868/f49d66bb9e61/JVM2014-584945.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68c1/4590868/8c18ae86c6b8/JVM2014-584945.003.jpg

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引用本文的文献

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Toxic Potential of Crude Extract From Cassava Cortex Containing Scopoletin and Cyanide on Wistar Rats and Broilers.含东莨菪亭和氰化物的木薯皮层粗提物对Wistar大鼠和肉鸡的毒性潜力
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