de Godoy Luciana B M, Palombini Luciana O, Guilleminault Christian, Poyares Dalva, Tufik Sergio, Togeiro Sonia M
Disciplina de Medicina e Biologia do Sono, Departamento de Psicobiologia, Universidade Federal de Sao Paulo, Sao Paulo, Brazil.
Stanford University Sleep Medicine Division, Redwood City, CA, USA.
Sleep Sci. 2015 Jan-Mar;8(1):42-8. doi: 10.1016/j.slsci.2015.03.001. Epub 2015 Mar 20.
To evaluate the available literature regarding Upper Airway Resistance Syndrome (UARS) treatment.
Keywords "Upper Airway Resistance Syndrome," "Sleep-related Breathing Disorder treatment," "Obstructive Sleep Apnea treatment" and "flow limitation and sleep" were used in main databases.
We found 27 articles describing UARS treatment. Nasal continuous positive airway pressure (CPAP) has been the mainstay therapy prescribed but with limited effectiveness. Studies about surgical treatments had methodological limitations. Oral appliances seem to be effective but their efficacy is not yet established.
Randomized controlled trials with larger numbers of patients and long-term follow-up are important to establish UARS treatment options.
评估关于上气道阻力综合征（UARS）治疗的现有文献。
在主要数据库中使用关键词“上气道阻力综合征”、“睡眠相关呼吸障碍治疗”、“阻塞性睡眠呼吸暂停治疗”以及“气流受限与睡眠”。
我们找到了27篇描述UARS治疗的文章。鼻持续气道正压通气（CPAP）一直是主要的规定治疗方法，但效果有限。关于手术治疗的研究存在方法学上的局限性。口腔矫治器似乎有效，但其疗效尚未确立。
开展有大量患者参与且进行长期随访的随机对照试验对于确定UARS的治疗方案很重要。
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