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邻苯二甲酸酯(邻苯二甲酸盐)、对羟基苯甲酸酯(对羟基苯甲酸酯)、双酚 A 二缩水甘油醚(BADGE)及其衍生物在越南室内灰尘中的出现:暴露风险的影响。

Occurrence of phthalate diesters (phthalates), p-hydroxybenzoic acid esters (parabens), bisphenol A diglycidyl ether (BADGE) and their derivatives in indoor dust from Vietnam: Implications for exposure.

机构信息

Wadsworth Center, New York State Department of Health, and Department of Environmental Health Sciences, School of Public Health, State University of New York at Albany, Empire State Plaza, P.O. Box 509, Albany, NY, 12201-0509, United States; Faculty of Chemistry, Hanoi University of Science, Vietnam National University, Hanoi, 19 Le Thanh Tong, Hoan Kiem, Hanoi, Vietnam.

Faculty of Chemistry, Hanoi University of Science, Vietnam National University, Hanoi, 19 Le Thanh Tong, Hoan Kiem, Hanoi, Vietnam.

出版信息

Chemosphere. 2016 Feb;144:1553-9. doi: 10.1016/j.chemosphere.2015.10.028. Epub 2015 Oct 26.

Abstract

Phthalate diesters (phthalates), esters of p-hydroxybenzoic acid (parabens), and bisphenol A diglycidyl ether (BADGE) are used in personal care products, food packages, household products, or pharmaceuticals. These compounds possess endocrine-disrupting potentials and have been reported to occur in the environment. Nevertheless, no previous studies have reported the occurrence of these compounds in indoor dust from Vietnam. In this study, nine phthalates, six parabens, and four BADGEs were determined in indoor dust samples collected from Hanoi, Hatinh, Hungyen, and Thaibinh, in Vietnam. Total concentrations of phthalates, parabens, and BADGEs in indoor dust ranged from 3440 to 106,000 ng/g (median: 22,600 ng/g), 40-840 ng/g (median: 123 ng/g), and 23 to 1750 ng/g (median: 184 ng/g), respectively. Based on the measured median concentration of phthalates, parabens, and BADGEs in indoor dust, we estimated human exposure doses to these compounds through indoor dust ingestion for various age groups. The exposure doses to phthalates, parabens, and BADGEs decreased with age and ranged from 19.4 to 90.4 ng/kg-bw/d, 0.113-0.528 ng/kg-bw/d, and 0.158-0.736 ng/kg-bw/d, respectively. This is the first study on the occurrence and human exposure of phthalates, parabens, and BADGEs in indoor dust from Vietnam.

摘要

酞酸酯(邻苯二甲酸酯)、对羟基苯甲酸酯(对羟基苯甲酸酯)和双酚 A 二缩水甘油醚(BADGE)用于个人护理产品、食品包装、家用产品或药品。这些化合物具有内分泌干扰潜力,并已报告在环境中存在。然而,以前没有研究报告过这些化合物在越南室内灰尘中的存在。在这项研究中,测定了来自越南河内、兴安、海阳和太平的室内灰尘样本中 9 种邻苯二甲酸酯、6 种对羟基苯甲酸酯和 4 种 BADGE。室内灰尘中邻苯二甲酸酯、对羟基苯甲酸酯和 BADGE 的总浓度范围为 3440 至 106,000ng/g(中位数:22,600ng/g)、40-840ng/g(中位数:123ng/g)和 23 至 1750ng/g(中位数:184ng/g)。根据室内灰尘中邻苯二甲酸酯、对羟基苯甲酸酯和 BADGE 的实测中位数浓度,我们估算了不同年龄组人群通过室内灰尘摄入这些化合物的暴露剂量。邻苯二甲酸酯、对羟基苯甲酸酯和 BADGE 的暴露剂量随年龄的增长而降低,范围分别为 19.4 至 90.4ng/kg-bw/d、0.113 至 0.528ng/kg-bw/d 和 0.158 至 0.736ng/kg-bw/d。这是首次研究越南室内灰尘中邻苯二甲酸酯、对羟基苯甲酸酯和 BADGE 的存在和人体暴露情况。

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