Karaman Erbil, Çetin Orkun, Kolusari Ali, Bayram Irfan
Assistant Professor, Department of Obstetric and Gynecology, School of Medicine, Yuzuncu Yil University , Van, Turkey .
Medical Doctor, Department of Obstetric and Gynecology, School of Medicine, Yuzuncu Yil University , Van, Turkey .
J Clin Diagn Res. 2015 Sep;9(9):QD17-8. doi: 10.7860/JCDR/2015/15828.6534. Epub 2015 Sep 1.
The primary tubal choriocarcinoma associated with ectopic pregnancy is very rare. A 31-year-old woman was admitted to the emergency room due to amenorrhea, left lower abdominal pain and fatigue. Her β-Hcg level was 29251.4 mIU/ml and transvaginal ultrasund revealed a 24x21 mm of left tubal ectopic pregancy mass with large amount of free fluid in pelvic cavity. The patient was diagnosed with ruptured tubal ectopic pregnancy and thus, she underwent laparotomy with left total salpingectomy. The pathological assessment was reported as primary tubal choriocarcinoma with the involvement of whole tubal layer. The patient was defined to have stage I choriocarcinoma with good prognostic factors and methotrexate monotherapy was administered. Serum β- Hcg levels of the patient gradually declined and eventually became negative at the first month of the treatment. With this case report we aimed to implicate that when diagnosing the ectopic pregnancy, even very rare, the tubal choriocarcinoma should be kept in mind.
与异位妊娠相关的原发性输卵管绒毛膜癌非常罕见。一名31岁女性因闭经、左下腹疼痛和乏力入住急诊室。她的β-Hcg水平为29251.4 mIU/ml,经阴道超声显示左侧输卵管异位妊娠包块大小为24x21 mm,盆腔内有大量游离液体。该患者被诊断为输卵管异位妊娠破裂,因此接受了剖腹手术及左侧输卵管全切术。病理评估报告为原发性输卵管绒毛膜癌,累及整个输卵管层。该患者被确定为具有良好预后因素的Ⅰ期绒毛膜癌,并接受了甲氨蝶呤单药治疗。患者的血清β-Hcg水平逐渐下降,在治疗的第一个月最终转为阴性。通过本病例报告,我们旨在表明,在诊断异位妊娠时,即使非常罕见,也应考虑到输卵管绒毛膜癌。