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1例脑干海绵状血管瘤切除术后的肥厚性橄榄体变性及文献复习

A case of hypertrophic olivary degeneration after resection of cavernomas of the brain stem and review of the literature.

作者信息

Zhang Meng, Ye Gengfan, Deng Lin, Xu Shuo, Wang Yunyan

机构信息

Department of Neurosurgery, Qi Lu Hospital, Shandong University, Jinan, People's Republic of China.

出版信息

Neuropsychiatr Dis Treat. 2015 Oct 8;11:2613-8. doi: 10.2147/NDT.S90549. eCollection 2015.

Abstract

Hypertrophic olivary degeneration is a transsynaptic form of degeneration, which is also a result of primary or secondary lesion and can damage the dento-rubro-olivary pathway. The dento-rubro-olivary pathway was first described by Guillain and Mollaret and is referred to as "the triangle of Guillain and Mollaret". Multiple factors can destroy the dento-rubro-olivary pathway, such as surgical operation, hemorrhage, tumor, trauma, inflammation, demyelination, degeneration, and radiation damage. All of the above factors can result in delayed hypertrophic olivary degeneration. Articles related to this disease cover etiology, clinical presentation, pathology changes, etc. However, to our knowledge, there has been no literature reporting the use of diffusion tensor imaging and diffusion tensor tractography to improve the diagnosis of hypertrophic olivary degeneration following resection of cavernomas in the brain stem. Herein, we report a case who was diagnosed with hypertrophic olivary degeneration following resection of cavernomas of the brain stem, verify the significance of diffusion tensor imaging and diffusion tensor tractography, and review previous literature. The development of imageology promotes and improves hypertrophic olivary degeneration diagnosis and differential diagnosis.

摘要

肥大性橄榄核变性是一种跨突触性变性形式,也是原发性或继发性病变的结果,可损害齿状红核橄榄束通路。齿状红核橄榄束通路最早由吉兰和莫拉雷描述,被称为“吉兰 - 莫拉雷三角”。多种因素可破坏齿状红核橄榄束通路,如外科手术、出血、肿瘤、创伤、炎症、脱髓鞘、变性和辐射损伤等。上述所有因素均可导致迟发性肥大性橄榄核变性。有关该疾病的文章涵盖病因、临床表现、病理变化等。然而,据我们所知,尚无文献报道使用扩散张量成像和扩散张量纤维束成像来改善脑干海绵状血管瘤切除术后肥大性橄榄核变性的诊断。在此,我们报告一例脑干海绵状血管瘤切除术后诊断为肥大性橄榄核变性的病例,验证扩散张量成像和扩散张量纤维束成像的意义,并回顾既往文献。影像学的发展促进并改善了肥大性橄榄核变性的诊断和鉴别诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/148f/4605241/2f6df99e4610/ndt-11-2613Fig1.jpg

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