创伤性脑损伤继发颅内感染的危险因素分析
Analysis on the risk factors of intracranial infection secondary to traumatic brain injury.
作者信息
Lin Chao, Zhao Xin, Sun Haichen
机构信息
Department of Neurosurgery, Jinling Hospital, Nanjing University, China.
出版信息
Chin J Traumatol. 2015;18(2):81-3. doi: 10.1016/j.cjtee.2014.10.007.
OBJECTIVE
To discuss the characteristics and risk factors for intracranial infection post traumatic brain injury to prevent and better the clinical care.
METHODS
Retrospective study of 520 patients with traumatic brain injury were included, 308 male and 212 female. The risky factors of intracranial infection were identified.
RESULTS
Thirty two cases (6.54%, 32/520) of intracranial infection were diagnosed. Intracranial infection most likely happened 4-10 days after injury. Cerebrospinal fluid leakage, drainage, multiple craniotomies were significant related to intracranial infection. Logistic regression predicted cerebrospinal fluid leakage and drainage as independent factors.
CONCLUSION
Intracranial infection is a serious complication after traumatic brain injury. Patients with drainage or cerebrospinal fluid leakage are more risky for intracranial infection. Aggressive precaution should be taken to better outcome.
目的
探讨创伤性脑损伤后颅内感染的特点及危险因素，以预防并改善临床护理。
方法
对520例创伤性脑损伤患者进行回顾性研究，其中男性308例，女性212例。确定颅内感染的危险因素。
结果
诊断出32例（6.54%，32/520）颅内感染。颅内感染最易发生在受伤后4至10天。脑脊液漏、引流、多次开颅手术与颅内感染显著相关。Logistic回归分析预测脑脊液漏和引流为独立因素。
结论
颅内感染是创伤性脑损伤后的严重并发症。有引流或脑脊液漏的患者发生颅内感染的风险更高。应采取积极预防措施以改善预后。
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