Godier Lauren R, Park Rebecca J
Oxford Brain-Body Research into Eating Disorders, Department of Psychiatry, University of Oxford Oxford, UK.
Front Psychol. 2015 Oct 20;6:1608. doi: 10.3389/fpsyg.2015.01608. eCollection 2015.
The characteristic relentless self-starvation behavior seen in Anorexia Nervosa (AN) has been described as evidence of compulsivity, with increasing suggestion of parallels with addictive behavior. This study used a thematic qualitative analysis to investigate the parallels between compulsive behavior in AN and Substance Use Disorders (SUD). Forty individuals currently suffering from AN completed an online questionnaire reflecting on their experience of compulsive behavior in AN. Eight main themes emerged from thematic qualitative analysis; compulsivity as central to AN, impaired control, escalating compulsions, emotional triggers, negative reactions, detrimental continuation of behavior, functional impairment, and role in recovery. These results suggested that individuals with AN view the compulsive nature of their behavior as central to the maintenance of their disorder, and as a significant barrier to recovery. The themes that emerged also showed parallels with the DSM-V criteria for SUDs, mapping onto the four groups of criteria (impaired control, social impairment, risky use of substance, pharmacological criteria). These results emphasize the need for further research to explore the possible parallels in behavioral and neural underpinnings of compulsivity in AN and SUDs, which may inform novel treatment avenues for AN.
神经性厌食症（AN）中典型的持续自我饥饿行为被描述为强迫行为的证据，越来越多的迹象表明它与成瘾行为存在相似之处。本研究采用主题定性分析法，探究神经性厌食症中的强迫行为与物质使用障碍（SUD）之间的相似之处。40名目前患有神经性厌食症的个体完成了一份在线问卷，反思他们在神经性厌食症中的强迫行为体验。主题定性分析得出了八个主要主题：强迫行为是神经性厌食症的核心、控制受损、强迫行为升级、情绪触发因素、负面反应、行为的有害持续、功能损害以及在康复中的作用。这些结果表明，患有神经性厌食症的个体认为其行为的强迫性质是维持其疾病的核心，也是康复的重大障碍。出现的主题还显示出与物质使用障碍的《精神疾病诊断与统计手册》第五版（DSM-V）标准存在相似之处，对应于四组标准（控制受损、社会功能损害、物质的危险使用、药理学标准）。这些结果强调需要进一步研究，以探索神经性厌食症和物质使用障碍中强迫行为在行为和神经基础方面可能存在的相似之处，这可能为神经性厌食症的新治疗途径提供信息。
