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男性导管原位癌(DCIS):这种罕见疾病的治疗策略

Male ductal carcinoma in situ (DCIS): treatment strategies in this rare entity.

作者信息

Aznan M S, Razrim R, Affirul C A, Rohaizak M

机构信息

Department of Surgery, Universiti Kebangsaan Malaysia, Jalan Yaacob Latiff, 56000, Kuala Lumpur, Malaysia.

Fakulti Perubatan, Universiti Sains Islam Malaysia, Jalan Pandan Utama, 55100, Kuala Lumpur, Malaysia.

出版信息

Clin Ter. 2015;166(5):e327-9. doi: 10.7417/T.2015.1887.

Abstract

Ductal carcinoma in situ (DCIS) in females is a recognized premalignant disease. However, its occurrence in males is rare. Articles describing this disease are scarce with documented occurrence is less than 7% worldwide. We report a case of 52 year-old gentleman presented with 6 months history of left breast lump. It was painless with no nipple discharge. Despite an inconclusive biopsy, lumpectomy was performed in view of the suspicion of malignant disease. Histopathology confirms DCIS. He underwent mastectomy and sentinel lymph nodes. Most treatment strategies are based on evidence on female breast malignancy and modifications are needed due to the different pathological pathway in male.

摘要

女性导管原位癌(DCIS)是一种公认的癌前疾病。然而,其在男性中的发生极为罕见。描述这种疾病的文章很少,全球有记录的发生率不到7%。我们报告一例52岁男性患者,有6个月左乳肿块病史。肿块无痛,无乳头溢液。尽管活检结果不明确,但鉴于怀疑为恶性疾病,仍进行了肿块切除术。组织病理学确诊为DCIS。他接受了乳房切除术和前哨淋巴结活检。大多数治疗策略基于女性乳腺恶性肿瘤的证据,由于男性不同的病理途径,需要进行调整。

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