Gaitán María I, Yañes Paulina, Sati Pascal, Romero Carlos, Reich Daniel S, Correale Jorge
Department of Neurology, Dr. Raúl Carrea Institute for Neurological Research, FLENI, Buenos Aires, Argentina
Department of Radiology, Dr. Raúl Carrea Institute for Neurological Research, FLENI, Buenos Aires, Argentina.
Mult Scler. 2016 Sep;22(10):1367-70. doi: 10.1177/1352458515615226. Epub 2015 Nov 9.
The infratentorial compartment is cardinal for multiple sclerosis (MS) diagnosis. T2-weighted (T2) and proton density-weighted (PD) magnetic resonance imaging (MRI) can visualize infratentorial lesions, but only suboptimally.
To combine PD and T2 for better lesion assessment.
T2 and PD from 35 cases were averaged to form "PT2" images. Two raters counted infratentorial lesions and qualitatively assessed their conspicuity.
PT2 showed 244 infratentorial lesions, of which 94% and 74% were seen in PD and T2. PT2 received higher grades for image quality and lesion conspicuity (p < 0.001 for all comparisons).
PT2 could improve our ability to diagnose and monitor MS.
幕下腔对于多发性硬化症(MS)的诊断至关重要。T2加权(T2)和质子密度加权(PD)磁共振成像(MRI)能够显示幕下病变,但效果欠佳。
将PD和T2相结合以更好地评估病变。
对35例患者的T2和PD图像进行平均以形成“PT2”图像。两名评估者对幕下病变进行计数并对其清晰度进行定性评估。
PT2显示出244个幕下病变,其中94%和74%分别在PD和T2图像中可见。PT2在图像质量和病变清晰度方面获得了更高的评分(所有比较的p值均<0.001)。
PT2能够提高我们诊断和监测MS的能力。