Mocioiu Victor, Ortega-Martorell Sandra, Olier Iván, Jablonski Michal, Starcukova Jana, Lisboa Paulo, Arús Carles, Julià-Sapé Margarida
Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, UAB, Cerdanyola del Vallès, Barcelona, 08193, Spain.
Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina CIBER-BBN, Cerdanyola del Vallès, Barcelona, Spain.
BMC Bioinformatics. 2015 Nov 9;16:378. doi: 10.1186/s12859-015-0796-5.
Magnetic resonance spectroscopy provides metabolic information about living tissues in a non-invasive way. However, there are only few multi-centre clinical studies, mostly performed on a single scanner model or data format, as there is no flexible way of documenting and exchanging processed magnetic resonance spectroscopy data in digital format. This is because the DICOM standard for spectroscopy deals with unprocessed data. This paper proposes a plugin tool developed for jMRUI, namely jMRUI2XML, to tackle the latter limitation. jMRUI is a software tool for magnetic resonance spectroscopy data processing that is widely used in the magnetic resonance spectroscopy community and has evolved into a plugin platform allowing for implementation of novel features.
jMRUI2XML is a Java solution that facilitates common preprocessing of magnetic resonance spectroscopy data across multiple scanners. Its main characteristics are: 1) it automates magnetic resonance spectroscopy preprocessing, and 2) it can be a platform for outputting exchangeable magnetic resonance spectroscopy data. The plugin works with any kind of data that can be opened by jMRUI and outputs in extensible markup language format. Data processing templates can be generated and saved for later use. The output format opens the way for easy data sharing- due to the documentation of the preprocessing parameters and the intrinsic anonymization--for example for performing pattern recognition analysis on multicentre/multi-manufacturer magnetic resonance spectroscopy data.
jMRUI2XML provides a self-contained and self-descriptive format accounting for the most relevant information needed for exchanging magnetic resonance spectroscopy data in digital form, as well as for automating its processing. This allows for tracking the procedures the data has undergone, which makes the proposed tool especially useful when performing pattern recognition analysis. Moreover, this work constitutes a first proposal for a minimum amount of information that should accompany any magnetic resonance processed spectrum, towards the goal of achieving better transferability of magnetic resonance spectroscopy studies.
磁共振波谱以非侵入性方式提供有关活体组织的代谢信息。然而,多中心临床研究很少,且大多是在单一扫描仪型号或数据格式上进行,因为目前尚无灵活的方式以数字格式记录和交换处理后的磁共振波谱数据。这是因为用于波谱分析的DICOM标准处理的是未处理的数据。本文提出了一种为jMRUI开发的插件工具,即jMRUI2XML,以解决后一个限制。jMRUI是一种用于磁共振波谱数据处理的软件工具,在磁共振波谱领域广泛使用,并已发展成为一个允许实现新功能的插件平台。
jMRUI2XML是一种Java解决方案,可促进跨多个扫描仪对磁共振波谱数据进行常规预处理。其主要特点是:1)它能自动进行磁共振波谱预处理,2)它可以作为输出可交换磁共振波谱数据的平台。该插件适用于任何能被jMRUI打开的数据,并以可扩展标记语言格式输出。可以生成并保存数据处理模板以供后续使用。由于预处理参数的记录和固有的匿名化处理,这种输出格式为轻松的数据共享开辟了道路——例如用于对多中心/多制造商的磁共振波谱数据进行模式识别分析。
jMRUI2XML提供了一种自包含且自描述的格式,涵盖了以数字形式交换磁共振波谱数据所需的最相关信息,以及实现其处理自动化。这允许追踪数据所经历的过程,这使得所提出的工具在进行模式识别分析时特别有用。此外,这项工作构成了关于任何经处理的磁共振波谱应附带的最少信息量的首个提议,朝着实现更好的磁共振波谱研究可转移性的目标迈进。