Wang Yong-jie, Zhang Jian-min
Department of Neurosurgery, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009 China.
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2015 Jul;44(4):361-5. doi: 10.3785/j.issn.1008-9292.2015.07.02.
Stroke classified into ischemic and hemorrhagic subtypes, is among the most devastating diseases for human being. Certain drugs could increase the blood viscosity, thereby increasing the potential risk of ischemia. Anti-platelet and anti-coagulation drugs, as the treatment of first choice, increase the risk of intracranial hemorrhage and death. Here, we are the first to propose the concept of drug-related stroke, and discuss the treatment strategy for patients who are complicated with intracranial hemorrhage or plan to receive neurosurgical operation during either anti-platelet or anti-coagulation medication. We hope to arouse the attention for drug related stroke among the clinicians and offer recommendation for clinical intervention.
中风分为缺血性和出血性亚型,是对人类最具毁灭性的疾病之一。某些药物会增加血液粘度,从而增加缺血的潜在风险。抗血小板和抗凝药物作为首选治疗方法,会增加颅内出血和死亡的风险。在此,我们首次提出药物相关性中风的概念,并讨论在抗血小板或抗凝治疗期间并发颅内出血或计划接受神经外科手术的患者的治疗策略。我们希望引起临床医生对药物相关性中风的关注,并为临床干预提供建议。