Edris Ahmad, Gordin Jonathan, Sallam Tamer, Wachsner Robin, Meymandi Sheba, Traina Mahmoud
Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE.
EuroIntervention. 2015 Nov;11(7):765-71. doi: 10.4244/EIJV11I7A153.
This study sought to evaluate the feasibility of a rapid deflation technique (RDT) after transradial catheterisation to achieve patent haemostasis and to assess whether this could reduce radial artery occlusion (RAO). Ensuring patent haemostasis is the most important factor in reducing RAO. The use of larger sheath sizes and antiplatelet and antithrombotic agents limits achieving patent haemostasis immediately after transradial intervention.
A feasibility assessment was first performed in 105 patients to assess whether RDT could be performed safely and consistently achieve patent haemostasis after transradial catheterisation. Prospective data were then collected on 201 patients who underwent either rapid or standard deflation technique and had RAO assessment at 24 hours. Acute coronary syndrome was the indication for transradial catheterisation in 62.7% of patients. Baseline patent haemostasis increased from 40% to 95% after RDT. RAO at 24 hours was seen in two (2.0%) patients in the RDT group and 15 (14.9%) in the standard deflation group (OR 0.117; 95% CI: 0.026 to 0.526, p=0.005). Other independent predictors of RAO included body surface area (OR 0.022; 95% CI: 0.002 to 0.273, p=0.003) and male sex (OR 0.298; 95% CI: 0.108 to 0.824, p=0.020). No significant difference was found in safety outcomes: need to re-inflate compression band (2% versus 1.8%) or haematoma (0% versus 0.9%).
Rapid deflation of the compression band after transradial catheterisation is a safe and effective method of achieving patent haemostasis that reduces RAO.
本研究旨在评估经桡动脉导管插入术后快速放气技术(RDT)实现止血且血流通畅的可行性,并评估其是否能减少桡动脉闭塞(RAO)。确保止血且血流通畅是减少RAO的最重要因素。使用较大尺寸的鞘管以及抗血小板和抗血栓药物会限制经桡动脉介入术后立即实现止血且血流通畅。
首先对105例患者进行可行性评估,以评估RDT是否能安全实施并在经桡动脉导管插入术后持续实现止血且血流通畅。然后收集了201例行快速或标准放气技术并在24小时时进行RAO评估的患者的前瞻性数据。62.7%的患者经桡动脉导管插入术的指征为急性冠状动脉综合征。RDT后基线止血且血流通畅率从40%提高到95%。RDT组2例(2.0%)患者在24小时时出现RAO,标准放气组有15例(14.9%)出现RAO(比值比0.117;95%置信区间:0.026至0.526,p = 0.005)。RAO的其他独立预测因素包括体表面积(比值比0.022;95%置信区间:0.002至0.273,p = 0.003)和男性(比值比0.298;95%置信区间:0.108至0.824,p = 0.020)。在安全结局方面未发现显著差异:需要重新充气压迫带(2%对1.8%)或血肿(0%对0.9%)。
经桡动脉导管插入术后快速放气压迫带是一种安全有效的实现止血且血流通畅的方法,可减少RAO。