ELF 诚实数据经纪人：信息学在竞争前领域促进公私合作。
The ELF Honest Data Broker: informatics enabling public-private collaboration in a precompetitive arena.
机构信息
Dassault Systemes, BIOVIA Ltd., 334 Cambridge Science Park, Cambridge CB4 0WN, UK.
Janssen EMEA, 2340 Turnhoutsweg 30, 2340 Beerse, Belgium; Finia Consulting Ltd, Unit 8 Dock Offices, Surrey Quays Road, London, SE16 2XU, UK.
出版信息
Drug Discov Today. 2016 Jan;21(1):97-102. doi: 10.1016/j.drudis.2015.11.005. Epub 2015 Nov 19.
New precompetitive ways of working in the pharmaceutical industry are driving the development of new informatics systems to enable their execution and management. The European Lead Factory (ELF) is a precompetitive, 30-partner collaboration between academic groups, small-medium enterprises and pharmaceutical companies created to discover small molecule hits against novel biological targets. A unique HTS screening and triage workflow has been developed to balance the intellectual property and scientific requirements of all the partners. Here, we describe the ELF Honest Data Broker, a cloud-based informatics system providing the scientific triage tools, fine-grained permissions and management tools required to implement the workflow.
制药行业的新的竞争前工作方式正在推动新的信息学系统的发展，以实现其执行和管理。欧洲先导工厂（ELF）是一个竞争前的、由 30 个合作伙伴组成的合作组织，由学术团体、中小企业和制药公司组成，旨在发现针对新型生物靶标的小分子命中。已经开发了一种独特的高通量筛选和分类工作流程，以平衡所有合作伙伴的知识产权和科学要求。在这里，我们描述了 ELF 诚实的数据经纪人，这是一个基于云的信息学系统，提供了实施该工作流程所需的科学分类工具、细粒度的权限和管理工具。
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