J Refract Surg. 2015 Dec;31(12):795-800. doi: 10.3928/1081597X-20151111-02.
To compare the objective and subjective quality of vision after femtosecond laser-assisted small incision lenticule extraction (SMILE) and laser-assisted subepithelial keratomileusis (LASEK) for mild to moderate myopia.
This prospective, comparative study included 65 eyes of 33 patients in the SMILE group, with a mean spherical equivalent (SE) of -4.16 ± 0.82 diopters, and 50 eyes of 25 patients in the LASEK group, with a mean SE of -3.81 ± 0.97 diopters. Visual acuity, corneal topography, contrast sensitivity, and wavefront aberrations were recorded preoperatively and compared with postoperative measurements. A quality of vision questionnaire was scored and analyzed 3 months postoperatively.
Three months postoperatively, the SMILE group had fewer (P < .05) higher-order aberrations (HOAs) (0.390 ± 0.175 µm), including spherical aberration (SA) (0.262 ± 0.242 µm), than the LASEK group (HOAs = 0.479 ± 0.148 µm, SA = 0.576 ± 0.287 µm, trefoil = 0.465 ± 0.248 µm). There was no significant difference in the amount of coma and trefoil between the two groups after surgery. Analysis of the scores of glare and halos in the quality of vision questionnaire revealed that SMILE (night glare = 1.25 ± 1.22, halos = 0.97 ± 1.12) provided a better quality of vision (P < .05) than LASEK (night glare = 2.32 ± 1.99, halos = 1.96 ± 1.77). The two groups demonstrated no significant difference in contrast sensitivity 3 months postoperatively. No vision-threatening complications were noted at any stage in either group.
Both SMILE and LASEK are safe and effective surgical procedures in the correction of myopia. SMILE has a lower induction rate of HOAs and a higher degree of patient satisfaction than LASEK at 3 months postoperatively.
比较飞秒激光小切口角膜基质透镜取出术(SMILE)和激光上皮下角膜磨镶术(LASEK)治疗轻度至中度近视的客观和主观视觉质量。
本前瞻性、对照研究纳入 33 例患者的 65 只眼(SMILE 组),平均等效球镜(SE)为-4.16±0.82 屈光度;25 例患者的 50 只眼(LASEK 组),平均 SE 为-3.81±0.97 屈光度。术前记录视力、角膜地形图、对比敏感度和波前像差,并与术后测量值进行比较。术后 3 个月对视觉质量问卷进行评分和分析。
术后 3 个月,SMILE 组的高阶像差(HOAs)(0.390±0.175 µm),包括球差(SA)(0.262±0.242 µm),低于 LASEK 组(HOAs=0.479±0.148 µm,SA=0.576±0.287 µm,彗差=0.465±0.248 µm,trefoil=0.465±0.248 µm,P<0.05)。术后两组的彗差和 trefoil 差异无统计学意义。视觉质量问卷中眩光和晕影评分分析显示,SMILE(夜间眩光=1.25±1.22,晕影=0.97±1.12)的视觉质量优于 LASEK(夜间眩光=2.32±1.99,晕影=1.96±1.77,P<0.05)。术后 3 个月两组对比敏感度差异无统计学意义。两组在任何阶段均未发生视力威胁性并发症。
SMILE 和 LASEK 都是治疗近视的安全有效的手术方法。SMILE 在术后 3 个月时诱导高阶像差的发生率较低,患者满意度较高。