一例罕见的咽后神经纤维瘤病例研究及文献综述

A rare case study of a retropharyngeal neurofibroma and a brief literature review.

作者信息

Atallah I, Gervasoni J, Gay E, Righini C A

机构信息

Clinique universitaire d'ORL, CHU de Grenoble, BP 217, 38042 Grenoble cedex 9, France; Université Joseph-Fourier, 621, avenue centrale, 38041 Saint-Martin-d'Hères, France; Inserm U823, BP 170, 38042 Grenoble cedex 9, France.

Clinique universitaire d'ORL, CHU de Grenoble, BP 217, 38042 Grenoble cedex 9, France; Département d'anatomie et cytologie pathologique, BP 217, 38042 Grenoble cedex 9, France.

出版信息

Eur Ann Otorhinolaryngol Head Neck Dis. 2016 Feb;133(1):47-50. doi: 10.1016/j.anorl.2015.11.003. Epub 2015 Dec 4.

DOI:10.1016/j.anorl.2015.11.003

PMID:26654695

Abstract

INTRODUCTION

Space occupying lesions in the retropharyngeal space are rare.

CASE REPORT

Here, we present a rare case of a retropharyngeal neurofibroma treated surgically through an open cervical approach without any complication.

DISCUSSION

Neurofibromas are benign, slowly growing neoplasms that could be associated or not with neurofibromatosis. They are derived from peripheral nerves. Diagnostic work-up should include CT-scan and MRI as well as a biopsy to confirm the diagnosis. Treatment of localized and diffuse neurofibromas is often surgical resection, which may require sacrifice of the nerve. Malignant transformation of these lesions, without association to NF-1, is rare and exceptionally documented in the literature.

CONCLUSION

We presented a rare case of solitary neurofibroma of the retropharyngeal space. Complete resection of the lesion was performed without any complication. We also presented a brief review of the literature about neurofibromas.

摘要