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尼日利亚化妆品中重金属的人体健康风险评估

Human health risk assessment of heavy metals in cosmetics in Nigeria.

作者信息

Nduka John K, Orisakwe Orish E, Ukaebgu Linda D, Sokaibe Chinwetuto, Udowelle Nnaemeka A

出版信息

J Cosmet Sci. 2015 Jul-Aug;66(4):233-46.

Abstract

Forty two different cosmetics were purchased from supermarkets and cosmetic shops within Unitsha Main Market and Eke-Awka markets in Anambra, Nigeria. Of the cosmetics, 16% were locally manufactured in Nigeria while 83.33% were imported into Nigeria. The cosmetics were ashed before digestion and filtration. The filtrates were assayed for lead, cadmium, manganese, nickel, chromium, mercury, and arsenic with atomic absorption spectrophotometry at 205 Å. The health risk assessment methods developed by the United States Environmental Protection Agency were employed to explore the potential human health risk of heavy metals in cosmetics. About 61.91% of the cosmetic samples contained lead with concentration in the range of 0.10-42.12 mg/kg. Cadmium levels of the cosmetics ranged from 0.01 to 1.32 mg/kg, manganese from 0.02 to 67.65 mg/kg, nickel from 0.05 to 17.34 mg/kg, chromium from 0.11 to 9.81 mg/kg, mercury from 0.003 to 0.07 mg/kg, and arsenic from 0.002 to 0.005 mg/kg. Although the target hazard quotients and the hazard indices suggest a measure of safety, cosmetics may add to the body burden of potential toxic metals after chronic exposure.

摘要

从尼日利亚阿南布拉州尤尼沙主市场和埃克 - 奥卡市场内的超市及化妆品店购买了42种不同的化妆品。这些化妆品中,16%是在尼日利亚本地生产的,而83.33%是进口到尼日利亚的。化妆品在消化和过滤前先进行灰化处理。滤液用原子吸收分光光度法在205 Å波长下测定铅、镉、锰、镍、铬、汞和砷的含量。采用美国环境保护局制定的健康风险评估方法来探究化妆品中重金属对人类潜在的健康风险。约61.91%的化妆品样品含有铅,浓度范围在0.10 - 42.12毫克/千克之间。化妆品中的镉含量在0.01至1.32毫克/千克之间,锰含量在0.02至67.65毫克/千克之间,镍含量在0.05至17.34毫克/千克之间,铬含量在0.11至9.81毫克/千克之间,汞含量在0.003至0.07毫克/千克之间,砷含量在0.002至0.005毫克/千克之间。尽管目标危害商数和危害指数表明有一定程度的安全性,但长期接触后,化妆品可能会增加人体潜在有毒金属的负担。

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