一氧化氮测量在哮喘以外临床病症中的应用。
Application of nitric oxide measurements in clinical conditions beyond asthma.
作者信息
Malinovschi Andrei, Ludviksdottir Dora, Tufvesson Ellen, Rolla Giovanni, Bjermer Leif, Alving Kjell, Diamant Zuzana
机构信息
Department of Medical Sciences: Clinical Physiology, Uppsala University, Uppsala, Sweden;
Department of Respiratory Medicine and Sleep, Landspitali University Hospital, Reykjavik, Iceland.
出版信息
Eur Clin Respir J. 2015 Aug 17;2:28517. doi: 10.3402/ecrj.v2.28517. eCollection 2015.
Abstract
Fractional exhaled nitric oxide (FeNO) is a convenient, non-invasive method for the assessment of active, mainly Th2-driven, airway inflammation, which is sensitive to treatment with standard anti-inflammatory therapy. Consequently, FeNO serves as a valued tool to aid diagnosis and monitoring in several asthma phenotypes. More recently, FeNO has been evaluated in several other respiratory, infectious, and/or immunological conditions. In this short review, we provide an overview of several clinical studies and discuss the status of potential applications of NO measurements in clinical conditions beyond asthma.
摘要
呼出一氧化氮分数（FeNO）是一种用于评估主要由Th2驱动的气道活动性炎症的便捷、非侵入性方法，对标准抗炎治疗敏感。因此，FeNO是辅助诊断和监测多种哮喘表型的重要工具。最近，FeNO已在其他几种呼吸系统、感染性和/或免疫性疾病中进行了评估。在这篇简短的综述中，我们概述了几项临床研究，并讨论了在哮喘以外的临床疾病中测量一氧化氮的潜在应用现状。
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本文引用的文献
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J Heart Lung Transplant. 2015 Apr;34(4):557-62. doi: 10.1016/j.healun.2014.09.026. Epub 2014 Nov 6.
2
Nasal nitric oxide screening for primary ciliary dyskinesia: systematic review and meta-analysis.
Eur Respir J. 2014 Dec;44(6):1589-99. doi: 10.1183/09031936.00088614. Epub 2014 Oct 16.
3
Characterization of airway inflammation in patients with COPD using fractional exhaled nitric oxide levels: a pilot study.
Int J Chron Obstruct Pulmon Dis. 2014 Jul 16;9:745-51. doi: 10.2147/COPD.S44552. eCollection 2014.
4
Effect of intubation and mechanical ventilation on exhaled nitric oxide in preterm infants with and without bronchopulmonary dysplasia measured at a median postmenstrual age of 49 weeks.
BMC Res Notes. 2014 Jun 24;7:389. doi: 10.1186/1756-0500-7-389.
5
Blood eosinophil guided prednisolone therapy for exacerbations of COPD: a further analysis.
Eur Respir J. 2014 Sep;44(3):789-91. doi: 10.1183/09031936.00062614. Epub 2014 Jun 12.
6
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Eur Respir J. 2014 Aug;44(2):341-50. doi: 10.1183/09031936.00216013. Epub 2014 May 29.
7
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Biomed Res Int. 2014;2014:271918. doi: 10.1155/2014/271918. Epub 2014 Feb 27.
8
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9
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J Thorac Dis. 2014 Mar;6 Suppl 1(Suppl 1):S146-51. doi: 10.3978/j.issn.2072-1439.2014.03.04.
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