Institut national de santé publique du Québec, Québec, Quebec, Canada.
Faculté de pharmacie, Université Laval, Québec, Quebec, Canada.
Health Promot Chronic Dis Prev Can. 2015 Dec;35(10):184-93. doi: 10.24095/hpcdp.35.10.02.
Of all cardiovascular causes of mortality, coronary heart disease (CHD) remains the leading cause of death. Our objectives were to establish trends in the prevalence and incidence of CHD in the province of Quebec, and to determine the proportion of CHD mortality that had no previous CHD diagnosis.
Trends in prevalence, incidence and mortality were examined with a population-based study using the Quebec Integrated Chronic Disease Surveillance System, which links several health administrative databases. Data are presented using two case definitions for Quebecers aged 20 years and over: 1) a validated definition, and 2) CHD causes of death codes added to estimate the proportion of deaths that occurred without any previous CHD diagnosis as a proxy for sudden cardiac death (SCD).
In 2012/2013, the crude prevalence of CHD was 9.4% with the first definition (593 000 people). Between 2000/2001 and 2012/2013, the age-standardized prevalence increased by 14%, although it has been decreasing slightly since 2009/2010. Age-standardized incidence and mortality rates decreased by 46% and 26% respectively, and represented a crude rate of 6.9 per 1000 and 5.2% in 2012/2013. The proportion identified only by CHD mortality, our SCD proxy, was only significant for the incident cases (0.38 per 1000 in 2009/2010) and declined over the study period.
The prevalence of CHD has tended to decrease in recent years, and incidence and mortality have been declining in Quebec. Most CHD mortality occurs in previously diagnosed patients and only a small proportion of incident cases were not previously identified.
在所有心血管疾病死因中,冠心病仍然是导致死亡的主要原因。我们的目的是确定魁北克省冠心病的患病率和发病率趋势,并确定无先前冠心病诊断的冠心病死亡率比例。
使用基于人群的研究,通过魁北克综合慢性疾病监测系统,将几个健康管理数据库联系起来,研究患病率、发病率和死亡率的趋势。数据采用两种魁北克 20 岁及以上人群的病例定义呈现:1)验证后的定义;2)增加冠心病死因代码,以估计无先前冠心病诊断的死亡比例,作为心源性猝死(SCD)的替代指标。
2012/2013 年,根据第一个定义,冠心病的粗患病率为 9.4%(593 万人)。2000/2001 年至 2012/2013 年期间,标准化患病率增加了 14%,尽管自 2009/2010 年以来略有下降。标准化发病率和死亡率分别下降了 46%和 26%,2012/2013 年的粗发病率和死亡率分别为每 1000 人 6.9 例和 5.2%。仅通过冠心病死亡率确定的比例,我们的 SCD 替代指标,仅对新发病例有显著意义(2009/2010 年为每 1000 人 0.38 例),并在研究期间呈下降趋势。
近年来,冠心病的患病率呈下降趋势,魁北克的发病率和死亡率也在下降。大多数冠心病死亡发生在先前诊断的患者中,只有一小部分新发病例以前未被发现。