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多学科疼痛中心治疗的慢性非恶性疼痛患者的人口统计学与健康相关生活质量之间的关联:一项队列研究。

Associations between demographics and health-related quality of life for chronic non-malignant pain patients treated at a multidisciplinary pain centre: a cohort study.

作者信息

Jensen Hanne Irene, Plesner Karin, Kvorning Nina, Krogh Bo Lunddal, Kimper-Karl Alan

机构信息

Department of Anaesthesiology and Intensive Care, Vejle and Middelfart Hospitals, Kabbeltoft 25, 7100 Vejle, Denmark Institute of Regional Health Research, University of Southern Denmark, J. B. Winsløws Vej 19, 5000 Odense C, Denmark.

Department of Anaesthesiology, Multidisciplinary Pain Centre, Vejle and Middelfart Hospitals, Østre Hougvej 55, 5500 Middelfart, Denmark Present address: Pain Centre, Odense University Hospital, Sdr. Boulevard 29, 5000 Odense C, Denmark.

出版信息

Int J Qual Health Care. 2016 Feb;28(1):86-91. doi: 10.1093/intqhc/mzv108. Epub 2015 Dec 17.

Abstract

OBJECTIVE

To describe the associations between demographics and health-related quality of life for chronic non-malignant pain patients.

DESIGN

A cohort study.

SETTING

A multidisciplinary Danish pain centre.

STUDY PARTICIPANTS

All patients treated at the centre between 2007 and 2013.

MAIN OUTCOME MEASURES

Levels of pain, anxiety and depression, and physical and mental status. The Hospital Anxiety and Depression Scale and the Medical Outcomes Study Short-Form Health Survey (SF-36) were used.

RESULTS

A total of 1176 patients were included. The majority were women (64%), the mean age was 46.7 ± 14.4 (range 18-89), and 21% were able to work full or part time. On a Numeric Rating Scale from 0 to 10, median pain-intensity was 8 (interquartile range 7-8) and pain-discomfort 8 (interquartile range 7-9) at time of referral. More than half of the patients had symptoms of anxiety and depression. Most of the individual SF-36 domains had median scores between 0 and 40 (Scale from 0 to 100). Patients younger than 50 years of age as well as patients on sick leave/disability pension had significantly lower SF-36 scores. Level of pain, anxiety and depression decreased and SF-36-scores increased significantly after a course of treatment which in most cases consisted of both medical, physiotherapeutic and psychological treatment as well as health-oriented education. The chi-square test, Mann-Whitney U-test, the Kruskal-Wallis and Wilcoxon Signed-rank test were used for analyses.

CONCLUSIONS

In order to improve treatment at a multidisciplinary pain centre, it may be of value to target treatments to different patient subgroups based on, amongst other things, age and employment status.

摘要

目的

描述慢性非恶性疼痛患者的人口统计学特征与健康相关生活质量之间的关联。

设计

队列研究。

地点

丹麦一家多学科疼痛中心。

研究参与者

2007年至2013年期间在该中心接受治疗的所有患者。

主要观察指标

疼痛、焦虑和抑郁水平以及身体和心理状况。使用医院焦虑抑郁量表和医学结局研究简明健康调查(SF - 36)。

结果

共纳入1176例患者。大多数为女性(64%),平均年龄为46.7±14.4岁(范围18 - 89岁),21%的患者能够全职或兼职工作。在0至10的数字评分量表上,转诊时疼痛强度中位数为8(四分位间距7 - 8),疼痛不适为8(四分位间距7 - 9)。超过一半的患者有焦虑和抑郁症状。大多数SF - 36单个领域的中位数得分在0至40之间(量表范围为0至100)。年龄小于50岁的患者以及休病假/领取残疾抚恤金的患者SF - 36得分显著较低。经过一个疗程的治疗后,疼痛、焦虑和抑郁水平降低,SF - 36得分显著提高,大多数情况下该疗程包括药物、物理治疗、心理治疗以及健康教育。采用卡方检验、曼 - 惠特尼U检验、克鲁斯卡尔 - 沃利斯检验和威尔科克森符号秩检验进行分析。

结论

为了改善多学科疼痛中心的治疗,根据年龄和就业状况等因素针对不同患者亚组进行治疗可能具有重要意义。

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