自然杀伤细胞与癌症：你可以教先天细胞新招。
NK cells and cancer: you can teach innate cells new tricks.
机构信息
Department of Microbiology and Immunology, University of California San Francisco, San Francisco, California 94143, USA.
出版信息
Nat Rev Cancer. 2016 Jan;16(1):7-19. doi: 10.1038/nrc.2015.5.
PMID:26694935
Abstract
Natural killer (NK) cells are the prototype innate lymphoid cells endowed with potent cytolytic function that provide host defence against microbial infection and tumours. Here, we review evidence for the role of NK cells in immune surveillance against cancer and highlight new therapeutic approaches for targeting NK cells in the treatment of cancer.
摘要
自然杀伤 (NK) 细胞是具有强大细胞溶解功能的固有淋巴细胞原型，为宿主提供了抵抗微生物感染和肿瘤的防御能力。在这里，我们回顾了 NK 细胞在癌症免疫监测中的作用的证据，并强调了针对 NK 细胞的新治疗方法在癌症治疗中的应用。
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