Wakabayashi Mami, McKetin Rebecca, Banwell Cathy, Yiengprugsawan Vasoontara, Kelly Matthew, Seubsman Sam-ang, Iso Hiroyasu, Sleigh Adrian
Public Health, Department of Social and Environmental Medicine, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita-shi, Osaka, 565-0871, Japan.
National Centre for Epidemiology and Population Health, Research School of Population Health, Australian National University, Canberra, Australia.
BMC Public Health. 2015 Dec 24;15:1297. doi: 10.1186/s12889-015-2662-9.
Heavy alcohol consumption is an established risk factor for non-communicable diseases (NCDs) but few studies have investigated drinking and disease risk in middle income, non-western countries. We report on the relationship between alcohol consumption and NCDs in Thailand.
A nationwide cross sectional survey was conducted of 87,151 Thai adult open university students aged 15 to 87 years (mean age 30.5 years) who were recruited into the Thai Cohort Study. Participants were categorized as never having drunk alcohol (n = 22,527), as being occasional drinkers who drank infrequently but heavily (4+ glasses/occasion - occasional heavy drinkers, n = 24,152) or drank infrequently and less heavily (<4 glasses/occasion - occasional light drinkers, n = 26,861). Current regular drinkers were subdivided into those who either drank heavily (4 + glasses per occasion - regular heavy drinkers, n = 3,675) or those who drank less (<4 glasses/occasion -regular light drinkers, n = 490). There were 7,548 ex-drinkers in the study. Outcomes were lifetime diagnoses of self-reported NCDs and obesity (body mass index ≥ 25).
Most women were never drinkers (40 % among females) or occasional light drinkers (39 %), in contrast to men (11 % and 22 %, respectively). Alcohol consumption was associated with urban in-migration and other recognized risks for NCDs (sedentary lifestyle and poor diet). After adjustment for these factors the odds ratios (ORs) for several NCDs outcomes - high cholesterol, hypertension, and liver disease - were significantly elevated among both occasional heavy drinkers (1.2 to 1.5) and regular heavy drinkers (1.5 to 2.0) relative to never drinkers.
Heavy alcohol consumption of 4 or more glasses per occasion, even if the occasions were infrequent, was associated with elevated risk of NCDs in Thailand. These results highlight the need for strategies in Thailand to reduce the quantity of alcohol consumed to prevent alcohol-related disease. Thailand is fortunate that most of the female population is culturally protected from drinking and this national public good should be endorsed and supported.
大量饮酒是已知的非传染性疾病(NCDs)风险因素,但很少有研究在中等收入的非西方国家调查饮酒与疾病风险的关系。我们报告泰国饮酒与非传染性疾病之间的关系。
对泰国队列研究招募的87151名15至87岁(平均年龄30.5岁)的泰国成年开放大学学生进行了全国性横断面调查。参与者被分为从不饮酒者(n = 22527)、偶尔大量饮酒者(每次饮酒4杯及以上,n = 24152)或偶尔少量饮酒者(每次饮酒少于4杯,n = 26861)。当前的经常饮酒者又细分为大量饮酒者(每次饮酒4杯及以上,n = 3675)或少量饮酒者(每次饮酒少于4杯,n = 490)。研究中有7548名戒酒者。结果是自我报告的非传染性疾病和肥胖症(体重指数≥25)的终生诊断情况。
大多数女性从不饮酒(占女性的40%)或偶尔少量饮酒(占39%),相比之下男性从不饮酒和偶尔少量饮酒的比例分别为11%和22%。饮酒与城市移民以及其他公认的非传染性疾病风险因素(久坐不动的生活方式和不良饮食)有关。在对这些因素进行调整后,与从不饮酒者相比,偶尔大量饮酒者(1.2至1.5)和经常大量饮酒者(1.5至2.0)中几种非传染性疾病——高胆固醇、高血压和肝病——的比值比(ORs)显著升高。
每次饮酒4杯及以上的大量饮酒,即使饮酒频率不高,在泰国也与非传染性疾病风险升高有关。这些结果凸显了泰国需要制定策略来减少饮酒量以预防与酒精相关的疾病。泰国很幸运,大多数女性在文化上受到保护不饮酒,这种国家公共利益应该得到认可和支持。