Lin Andrew L, Avila Edward K
1 Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
J Intensive Care Med. 2017 Feb;32(2):99-115. doi: 10.1177/0885066615619582. Epub 2016 Jul 9.
Neurologic complications of cancer are common and are frequently life-threatening events. Certain neurologic emergencies occur more frequently in the cancer population, specifically elevated intracranial pressure, epidural cord compression, status epilepticus, ischemic and hemorrhagic stroke, central nervous system infection, and treatment-associated neurologic dysfunction. These emergencies require early diagnosis and prompt treatment to ensure the best possible outcome and are best managed in the intensive care unit. This article reviews the presentation, pathophysiology, and management of the most common causes of acute neurologic decompensation in the patient with cancer.
癌症的神经系统并发症很常见,且常常是危及生命的事件。某些神经系统急症在癌症患者中更为常见,特别是颅内压升高、硬膜外脊髓压迫、癫痫持续状态、缺血性和出血性中风、中枢神经系统感染以及治疗相关的神经功能障碍。这些急症需要早期诊断和及时治疗以确保最佳预后,在重症监护病房进行管理最为适宜。本文综述了癌症患者急性神经功能失代偿最常见病因的临床表现、病理生理学及管理。