Fung Enrica, Kurella Tamura Manjula
Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA; and VA Palo Alto Geriatric Research and Education Clinical Center, Palo Alto, CA.
Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA; and VA Palo Alto Geriatric Research and Education Clinical Center, Palo Alto, CA.
Adv Chronic Kidney Dis. 2016 Jan;23(1):8-11. doi: 10.1053/j.ackd.2015.10.001.
CKD is increasingly common in older adults. Estimating the glomerular filtration rate can be challenging in this population, with sarcopenia affecting the accuracy of various formulae. Competing risks of death influence the risk of progression to end-stage kidney disease. In managing CKD in this population, one must take into consideration other comorbidities including assessment of geriatric syndromes. More research is still needed to guide medical management in this heterogeneous population.
慢性肾脏病(CKD)在老年人中越来越常见。在这一人群中估算肾小球滤过率可能具有挑战性,因为肌肉减少症会影响各种公式的准确性。相互竞争的死亡风险会影响进展至终末期肾病的风险。在管理这一人群的CKD时,必须考虑其他合并症,包括老年综合征的评估。仍需要更多研究来指导这一异质性人群的医疗管理。