Khorana Jiraporn, Singhavejsakul Jesda, Ukarapol Nuthapong, Laohapensang Mongkol, Wakhanrittee Junsujee, Patumanond Jayanton
Division of Pediatric Surgery, Department of Surgery, Chiang Mai University Hospital, Chiang Mai, Thailand.
Division of Gastroenterology, Department of Pediatrics, Chiang Mai University Hospital, Chiang Mai, Thailand.
Ther Clin Risk Manag. 2015 Dec 15;11:1837-42. doi: 10.2147/TCRM.S92169. eCollection 2015.
Intussusception is a common surgical emergency in infants and children. The incidence of intussusception is from one to four per 2,000 infants and children. If there is no peritonitis, perforation sign on abdominal radiographic studies, and nonresponsive shock, nonoperative reduction by pneumatic or hydrostatic enema can be performed. The purpose of this study was to compare the success rates of both the methods.
Two institutional retrospective cohort studies were performed. All intussusception patients (ICD-10 code K56.1) who had visited Chiang Mai University Hospital and Siriraj Hospital from January 2006 to December 2012 were included in the study. The data were obtained by chart reviews and electronic databases, which included demographic data, symptoms, signs, and investigations. The patients were grouped according to the method of reduction followed into pneumatic reduction and hydrostatic reduction groups with the outcome being the success of the reduction technique.
One hundred and seventy episodes of intussusception occurring in the patients of Chiang Mai University Hospital and Siriraj Hospital were included in this study. The success rate of pneumatic reduction was 61% and that of hydrostatic reduction was 44% (P=0.036). Multivariable analysis and adjusting of the factors by propensity scores were performed; the success rate of pneumatic reduction was 1.48 times more than that of hydrostatic reduction (P=0.036, 95% confidence interval [CI] =1.03-2.13).
Both pneumatic and hydrostatic reduction can be performed safely according to the experience of the radiologist or pediatric surgeon and hospital setting. This study showed that pneumatic reduction had a higher success rate than hydrostatic reduction.
肠套叠是婴幼儿常见的外科急症。肠套叠的发病率为每2000名婴幼儿中有1至4例。如果没有腹膜炎、腹部影像学检查显示的穿孔迹象以及无反应性休克,可通过空气灌肠或水压灌肠进行非手术复位。本研究的目的是比较两种方法的成功率。
进行了两项机构回顾性队列研究。纳入了2006年1月至2012年12月期间就诊于清迈大学医院和诗里拉吉医院的所有肠套叠患者(国际疾病分类第十版代码K56.1)。数据通过病历审查和电子数据库获取,包括人口统计学数据、症状、体征和检查结果。根据复位方法将患者分为空气灌肠复位组和水压灌肠复位组,结果为复位技术的成功与否。
本研究纳入了清迈大学医院和诗里拉吉医院患者发生的170例肠套叠病例。空气灌肠复位的成功率为61%,水压灌肠复位的成功率为44%(P = 0.036)。进行了多变量分析并通过倾向评分对因素进行了调整;空气灌肠复位的成功率比水压灌肠复位高1.48倍(P = 0.036,95%置信区间[CI] = 1.03 - 2.13)。
根据放射科医生或小儿外科医生的经验以及医院的情况,空气灌肠和水压灌肠复位均可安全进行。本研究表明,空气灌肠复位的成功率高于水压灌肠复位。