Ferguson John
J Drugs Dermatol. 2016 Jan;15(1):55-8.
Radiofrequency has long been successfully employed for medical and, more recently, aesthetic indications due to its ability to cause tissue contraction by thermal induction of neocollagenesis and the subsequent wound healing cascade, leading to collagen remodeling and a tightening effect. Percutaneous RF treatment provides therapeutically relevant thermal stimulation directly to the tissue target in a minimally invasive manner, which is therapeutically ideal because of limitations inherent in transcutaneous RF heating. A novel device combines percutaneous RF with thermistor-controlled temperature regulation and external tissue temperature monitoring, providing the ability to safely deliver RF energy.
Percutaneous subdermal RF treatment was performed on 48 samples of abdominoplasty tissue; samples were marked to standardize measurement of surface area in the treatment zones, and a subdermal temperature target of 51°C was preprogrammed into the treatment device. The treatment cannula was inserted parallel to the dermal plane at four points with a single pass per insertion. Surface area was then re-measured.
Approximate average reduction in surface area was 91.23±19.33 mm2, ranging between 124.45 mm2 and 35.39 mm2 (median 96.83 mm2). Results were statistically significant (P<0.0001). Statistical analysis via analysis of variance (ANOVA) plus Tukey post-hoc testing revealed no statistically significant difference between the sides in all comparisons, demonstrating symmetry in contracture.
Percutaneous subdermal monopolar RF creates dramatic, immediate tissue contraction in vitro and is a viable technology for tissue tightening.
长期以来,射频因其能够通过热诱导新胶原形成及随后的伤口愈合级联反应引起组织收缩,从而导致胶原重塑和紧致效果,已成功应用于医学领域,最近还用于美容适应症。经皮射频治疗以微创方式直接向组织靶点提供具有治疗意义的热刺激,由于经皮射频加热存在固有局限性,所以这在治疗上是理想的。一种新型设备将经皮射频与热敏电阻控制的温度调节及外部组织温度监测相结合,能够安全地输送射频能量。
对48份腹壁成形术组织样本进行经皮皮下射频治疗;对样本进行标记以标准化治疗区域表面积的测量,并将皮下温度目标设定为51°C预编程到治疗设备中。治疗套管在四个点平行于真皮平面插入,每次插入单次通过。然后重新测量表面积。
表面积的近似平均减少量为91.23±19.33平方毫米,范围在124.45平方毫米至35.39平方毫米之间(中位数96.83平方毫米)。结果具有统计学意义(P<0.0001)。通过方差分析(ANOVA)加Tukey事后检验的统计分析显示,所有比较中两侧之间无统计学显著差异,表明挛缩具有对称性。
经皮皮下单极射频在体外可产生显著的即时组织收缩,是一种可行的组织紧致技术。