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伊朗儿童白喉-破伤风-百日咳疫苗接种延迟比例概率的风险因素;生命表法分析

Risk Factors of Delay Proportional Probability in Diphtheria-tetanus-pertussis Vaccination of Iranian Children; Life Table Approach Analysis.

作者信息

Mokhtari Mohsen, Rezaeimanesh Masoomeh, Mohammadbeigi Abolfazl, Zahraei Seyed Mohsen, Mohammadsalehi Narges, Ansari Hossein

机构信息

Department of Diseases Control, Health Vic Chancellor, Arak University of Medical Sciences, Arak, Iran.

Department of Epidemiology and Biostatistics, School of Health, Qom University of Medical Sciences, Qom, Iran.

出版信息

J Glob Infect Dis. 2015 Oct-Dec;7(4):165-9. doi: 10.4103/0974-777X.170503.

Abstract

Despite success in expanded program immunization for an increase in vaccination coverage in the children of world, timeliness and schedule of vaccination remains as one of the challenges in public health. This study purposed to demonstrate the related factors of delayed diphtheria-tetanus-pertussis (DTP) vaccination using life table approach. A historical cohort study conducted in the poor areas of five large Iran cities. Totally, 3610 children with 24-47 months old age who had documented vaccination card were enrolled. Time of vaccination for the third dose of DTP vaccine was calculated. Life table survival was used to calculate the proportional probability of vaccination in each time. Wilcoxon test was used for the comparison proportional probability of delayed vaccination based on studies factors. The overall median delayed time for DTP3 was 38.52 days. The Wilcoxon test showed that city, nationality, education level of parents, birth order and being in rural areas are related to the high probability of delay time for DTP3 vaccination (P < 0. 001). Moreover, child gender and parent's job were not significant factors (P > 0.05). Being away from the capital, a high concentration of immigrants in the city borders with a low socioeconomic class leads to prolonged delay in DTP vaccination time. Special attention to these areas is needed to increase the levels of parental knowledge and to facilitate access to the health services care.

摘要

尽管扩大免疫规划在提高全球儿童疫苗接种覆盖率方面取得了成功,但疫苗接种的及时性和接种计划仍然是公共卫生面临的挑战之一。本研究旨在采用生命表法证明白喉-破伤风-百日咳(DTP)疫苗接种延迟的相关因素。在伊朗五个大城市的贫困地区进行了一项历史性队列研究。总共纳入了3610名年龄在24至47个月且有疫苗接种记录卡的儿童。计算了DTP疫苗第三剂的接种时间。使用生命表生存法计算每次接种的比例概率。采用Wilcoxon检验根据研究因素比较延迟接种的比例概率。DTP3的总体中位延迟时间为38.52天。Wilcoxon检验表明,城市、国籍、父母教育水平、出生顺序和是否在农村地区与DTP3疫苗接种延迟时间的高概率相关(P < 0.001)。此外,儿童性别和父母职业不是显著因素(P > 0.05)。远离首都、城市边境地区移民集中且社会经济阶层较低导致DTP疫苗接种时间延长。需要特别关注这些地区,以提高家长知识水平并促进获得卫生服务护理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/861a/4693308/ab156226a86f/JGID-7-165-g002.jpg

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