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[不同盐类及不同膳食成分中氟化物的生物利用度]

[Bioavailability of fluorides from various salts and from various dietary components].

作者信息

Patz J, Henschler D, Fickenscher H

出版信息

Dtsch Zahnarztl Z. 1977 Jun;32(6):482-6.

PMID:267572
Abstract

In six male subjects fluoride bio-availability after oral application of NaF and MgF2 was examined and the influence of food on fluoride absorption was studied by recording fluoride level in plasma and parotid saliva for 24 hours. In addition, fluoride profiles in the plasma of four beagle dogs after the intake of fluoride as NaF, MgF2 and CaF2 with and without addition of milk and dairy products were established. There were great differences in extent and speed of absorption among the different preparations some of which were demonstrated not to release fluoride at all. As was expected, absorption was quicker and more complete in patients with empty stomach than with simultaneous food intake. Milk and dairy products delay fluoride uptake without considerably reducing the overally amount of fluoride resorption.

摘要

对6名男性受试者口服氟化钠(NaF)和氟化镁(MgF2)后的氟生物利用度进行了检测,并通过记录24小时血浆和腮腺唾液中的氟水平,研究了食物对氟吸收的影响。此外,还测定了4只比格犬在摄入含或不含牛奶及奶制品的NaF、MgF2和CaF2后血浆中的氟分布情况。不同制剂在吸收程度和速度上存在很大差异,其中一些制剂根本不释放氟。正如预期的那样,空腹患者的氟吸收比同时进食时更快、更完全。牛奶和奶制品会延迟氟的吸收,但不会显著减少氟的总体吸收量。

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