骨强度：不仅仅是骨密度。
Bone strength: more than just bone density.
机构信息
Department of Medicine, University of Washington, Seattle, Washington, USA.
出版信息
Kidney Int. 2016 Jan;89(1):16-9. doi: 10.1016/j.kint.2015.11.004.
The following bone density measurements have limited utility in determining bone strength because they do not include bone quality: microarchitecture, mineralization, ability to repair damage, collagen structure, crystal size, or marrow composition. Patients with kidney disease have poor bone quality. Newman et al. now describe beneficial effects with raloxifene in an animal model of progressive kidney disease. These biomechanical measurements will be important in the development of medications to decrease fractures in patients.
以下骨密度测量在确定骨强度方面的作用有限，因为它们不包括骨质量：微观结构、矿化、损伤修复能力、胶原结构、晶体尺寸或骨髓成分。患有肾脏疾病的患者骨质量较差。Newman 等人现在在进行性肾病动物模型中描述了雷洛昔芬的有益作用。这些生物力学测量在开发减少患者骨折的药物方面将非常重要。
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