Cunningham A J
Department of Anaesthesia, Royal College of Surgeons, Dublin, Ireland.
Can J Anaesth. 1989 Sep;36(5):568-77. doi: 10.1007/BF03005388.
Patients presenting for abdominal aortic surgery have a high incidence of vascular disease elsewhere, manifested primarily by hypertension, coronary and cerebrovascular disease, as well as co-existing respiratory, renal and metabolic disorders. Routine clinical assessment, electrocardiogram, chest roentgenograms, resting and exercise radionuclide ventriculography and echocardiography, dipyrdiamole-thallium scanning are all designed to assess the functional status of the myocardium and to detect the presence of significant coronary artery disease. Patients with no abnormalities on physical examination, routine evaluation and no redistribution on dipyridamole-thallium scanning should proceed to surgery with the expectation of very low perioperative cardiac risk. Patients with evidence of coronary artery disease and significant redistribution on dipyridamole-thallium scan should undergo coronary angiography and possible myocardial revascularization before definitive aortic vascular surgery. For high cardiac risk patients with no bypassable lesions presenting for abdominal aortic aneurysm resection a conservative policy of serial three monthly ultrasound or CT assessment may be adopted, with selective resection for rapid aneurysm expansion or symptom development. A variety of extra-anatomical and angioplastic techniques is available for similar high cardiac risk patients with aortoiliac occlusive disease. The haemodynamic consequences of aortic cross-clamping, especially in aneurysm patients, include a significant reduction in stroke volume, cardiac index, and myocardial oxygen consumption with an increased systemic vascular resistance. Patients with coronary artery disease may respond to aortic cross-clamping by increasing pulmonary capillary wedge pressure and by demonstrating ECG evidence of myocardial ischaemia. Pulmonary artery catheterization is especially indicated in patients with a history of previous myocardial infarction, angina or signs of cardiac failure and in patients with evidence of diminished ejection fraction, abnormal ventricular wall motion or myocardial redistribution on preoperative scanning. The more widespread application of intraoperative transoesophageal two-dimensional echocardiography and radionuclide cardiography monitoring techniques into anaesthetic practice will enable measurement of left ventricular dimensions, myocardial performance and wall motion. Suggested guidelines for anaesthetic management are presented in Table VI. A combined opiate-oxygen-volatile anaesthetic agent technique will best ensure a hypodynamic circulation with preservation of myocardial oxygenation.(ABSTRACT TRUNCATED AT 400 WORDS)
接受腹主动脉手术的患者,其他部位血管疾病的发生率很高,主要表现为高血压、冠状动脉和脑血管疾病,以及并存的呼吸、肾脏和代谢紊乱。常规临床评估、心电图、胸部X线片、静息和运动放射性核素心室造影及超声心动图、双嘧达莫-铊扫描,都是为了评估心肌的功能状态并检测是否存在严重冠状动脉疾病。体格检查、常规评估无异常且双嘧达莫-铊扫描无再分布的患者,可进行手术,预期围手术期心脏风险极低。双嘧达莫-铊扫描有冠状动脉疾病证据且有明显再分布的患者,在确定性主动脉血管手术前应进行冠状动脉造影及可能的心肌血运重建。对于因腹主动脉瘤切除术就诊且无可搭桥病变的高心脏风险患者,可采用每三个月进行一次超声或CT连续评估的保守策略,在动脉瘤快速扩张或出现症状时进行选择性切除。对于患有主髂动脉闭塞性疾病的类似高心脏风险患者,有多种解剖外和血管成形技术可供选择。主动脉阻断的血流动力学后果,尤其是在动脉瘤患者中,包括心搏量、心脏指数和心肌氧耗量显著降低,同时全身血管阻力增加。冠状动脉疾病患者可能会因主动脉阻断而出现肺毛细血管楔压升高,并出现心电图显示的心肌缺血证据。肺动脉导管插入术特别适用于有心肌梗死病史、心绞痛或心力衰竭体征的患者,以及术前扫描显示射血分数降低、心室壁运动异常或心肌再分布的患者。术中经食管二维超声心动图和放射性核素心脏监测技术在麻醉实践中的更广泛应用,将能够测量左心室大小、心肌性能和壁运动。麻醉管理的建议指南见表六。联合使用阿片类药物-氧气-挥发性麻醉剂技术将最能确保低动力循环并维持心肌氧合。(摘要截取自400字)