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葡萄牙首例冷冻保存10年的卵巢组织移植:一个意外的适应症。

First transplantation of cryopreserved ovarian tissue in Portugal, stored for 10 years: an unexpected indication.

作者信息

Póvoa Ana, Xavier Pedro, Calejo Lucinda, Soares Sandra, Sousa Mário, Silva Joaquina, Sousa Sónia, Barros Alberto, Beires Jorge

机构信息

Unit of Reproductive Medicine, Department of Gynecology and Obstetrics, Hospital Center São João, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal.

Unit of Reproductive Medicine, Department of Gynecology and Obstetrics, Hospital Center São João, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal.

出版信息

Reprod Biomed Online. 2016 Mar;32(3):334-6. doi: 10.1016/j.rbmo.2015.12.002. Epub 2015 Dec 24.

Abstract

Ovarian tissue cryopreservation represents a valid strategy to preserve ovarian function in patients with a high risk of premature ovarian failure. We present a case of ovarian tissue cryopreservation carried out in an 18-year-old woman after a laparotomy for left adnexal mass with left adnexectomy. Congenital absence of the right ovary was observed during surgery. To preserve fertility, rescue cryopreservation of ovarian tissue was carried out under extreme conditions (without adopting the standard published protocol, not yet available at our centre). Ten years later, transplantation of cryopreserved ovarian tissue was carried out and, shortly after it, restoration of ovarian function was confirmed.

摘要

卵巢组织冷冻保存是一种在卵巢早衰高危患者中保存卵巢功能的有效策略。我们报告一例18岁女性在因左侧附件肿物行剖腹探查及左侧附件切除术后进行卵巢组织冷冻保存的病例。手术中发现右侧卵巢先天性缺如。为保留生育能力,在极端条件下(未采用已发表的标准方案,我们中心当时尚无该方案)进行了卵巢组织的抢救性冷冻保存。十年后,进行了冷冻保存卵巢组织的移植,术后不久证实卵巢功能恢复。

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