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反流性疾病的病态肥胖患者可以接受腹腔镜袖状胃切除术吗?40例病例报告

Can morbidly obese patients with reflux be offered laparoscopic sleeve gastrectomy? A case report of 40 patients.

作者信息

Hawasli Abdelkader, Reyes Michael, Hare Bradley, Meguid Ahmed, Harriott Alwyn, Almahmeed Taghreed, Thatimatla Naga, Szpunar Susanna

机构信息

Department of Surgery, St. John Hospital and Medical Center, Detroit, MI, USA; Department of Surgery, Beaumont Hospital, Grosse Pointe, MI, USA.

Department of Surgery, St. John Hospital and Medical Center, Detroit, MI, USA.

出版信息

Am J Surg. 2016 Mar;211(3):571-6. doi: 10.1016/j.amjsurg.2015.11.006. Epub 2015 Dec 23.

Abstract

BACKGROUND

The incidence of reflux in obesity can reach greater than 35%. Most surgeons recommend Roux-en-y gastric bypass to patients with pre-existing reflux. One alternative to Roux-en-y gastric bypass is the addition of anterior fundoplication (AF) with posterior crural approximation (pCA) to laparoscopic sleeve gastrectomy (LSG) in patients with documented reflux.

METHODS

Between February 2011 and April 2013 we reviewed data from the bariatric registry on weight loss, resolution of symptoms, and quality of life presurgery and postsurgery for all patients who consented to participate in the registry and underwent LSG with AF/pCA.

RESULTS

Forty patients met inclusion criteria; 78% (31) were female. The mean initial weight was 298 ± 64 lbs. with mean BMI of 49 ± 8 kg/m(2). The mean DeMeester score was 36 ± 27 (normal <14.7). Nine (22.5%) patients had esophagitis. Thirty-six (90%) patients had hiatal hernia. There were no intraoperative complications. The mean operative time was 84 ± 20 minutes and the mean hospital stay was 1.6 ± .9 days. Postoperative complications included 1 fluid collection, 1 narrowing, 4 admissions for nausea and dehydration, 1 for pancreatitis, and 1 for deep vein thrombosis . Thirty-eight (95%) patients had immediate resolution of reflux, whereas 2 (5%) patients complained of worsening symptoms. On short-term follow-up of 24 ± 6 months, 55% of patients responded to the gastroesophageal reflux disease-health related quality of life questionnaire with improvement in their median score from 31/75 interquartile range (IQR 25) preoperatively to 0/75 (IQR 6.5) postoperatively (P < .0001). Their %excess body mass index loss was 69 ± 27%.

CONCLUSIONS

Morbidly obese patients with documented reflux can be offered LSG with the addition of AF/pCA.

摘要

背景

肥胖症患者中反流的发生率可超过35%。大多数外科医生建议为已有反流症状的患者施行Roux-en-y胃旁路手术。对于有反流记录的患者,Roux-en-y胃旁路手术的一种替代方案是在腹腔镜袖状胃切除术(LSG)基础上加做前壁胃底折叠术(AF)和后壁脚缝缩术(pCA)。

方法

2011年2月至2013年4月期间,我们回顾了肥胖症登记处的数据,这些数据涉及所有同意参与登记并接受了LSG联合AF/pCA手术的患者术前及术后的体重减轻情况、症状缓解情况和生活质量。

结果

40例患者符合纳入标准;78%(31例)为女性。平均初始体重为298±64磅,平均体重指数为49±8kg/m²。平均DeMeester评分为36±27(正常<14.7)。9例(22.5%)患者有食管炎。36例(90%)患者有食管裂孔疝。术中无并发症。平均手术时间为84±20分钟,平均住院时间为1.6±0.9天。术后并发症包括1例积液、1例狭窄、4例因恶心和脱水入院、1例因胰腺炎入院和1例因深静脉血栓形成入院。38例(95%)患者的反流症状立即缓解,而2例(5%)患者抱怨症状加重。在24±6个月的短期随访中,55%的患者对胃食管反流病-健康相关生活质量问卷做出了回应,其评分中位数从术前的31/75四分位间距(IQR 25)改善至术后的0/75(IQR 6.5)(P<.0001)。他们的%超重体重指数损失为69±27%。

结论

对于有反流记录的病态肥胖患者,可以提供加做AF/pCA的LSG手术。

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