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J-CTO评分对慢性完全闭塞病变经皮冠状动脉介入治疗后手术结果及靶病变血运重建的影响:J-CTO注册研究(日本多中心CTO注册研究)的一项子研究

Impact of J-CTO score on procedural outcome and target lesion revascularisation after percutaneous coronary intervention for chronic total occlusion: a substudy of the J-CTO Registry (Multicentre CTO Registry in Japan).

作者信息

Tanaka Hiroyuki, Morino Yoshihiro, Abe Mitsuru, Kimura Takeshi, Hayashi Yasuhiko, Muramatsu Toshiya, Ochiai Masahiko, Noguchi Yuichi, Kato Kenichi, Shibata Yoshisato, Hiasa Yoshikazu, Doi Osamu, Yamashita Takehiro, Morimoto Takeshi, Hinohara Tomoaki, Fujii Toshiharu, Mitsudo Kazuaki

机构信息

Kurashiki Central Hospital, Kurashiki, Japan.

出版信息

EuroIntervention. 2016 Jan 22;11(9):981-8. doi: 10.4244/EIJV11I9A202.

Abstract

AIMS

We investigated the impact of the J-CTO score, a pre-procedural risk score for successful guidewire crossing within 30 minutes through chronic total occlusion (CTO) lesions, on procedural and midterm clinical outcomes in terms of target lesion revascularisation (TLR) after CTO recanalisation.

METHODS AND RESULTS

The primary endpoint of this substudy was midterm TLR. The net midterm success rate was calculated by multiplying the lesion success rate by the TLR-free survival rate. The initial lesion success rates according to the J-CTO score categories of 0, 1, 2, and ≥3 were 97.0%, 92.1%, 86.5%, and 73.6%, respectively (p<0.001). The TLR rates at one year according to the J-CTO score categories of 0, 1, 2, and ≥3 were 5.3%, 11.1%, 16.7%, and 13.4%, respectively (p=0.082). The net midterm success rates according to the J-CTO score categories of 0, 1, 2, and ≥3 were 91.9%, 81.9%, 72.1%, and 63.7%, respectively (p<0.001).

CONCLUSIONS

Patients with CTO lesions with lower J-CTO scores are expected to achieve a high procedural success rate and an increased TLR-free survival rate. Patients with high J-CTO scores still remain an issue.

摘要

目的

我们研究了J-CTO评分(一种用于评估在30分钟内成功通过慢性完全闭塞(CTO)病变的导丝的术前风险评分)对CTO再通术后靶病变血管重建(TLR)方面的手术及中期临床结局的影响。

方法与结果

本亚组研究的主要终点是中期TLR。净中期成功率通过将病变成功率乘以无TLR生存率来计算。根据J-CTO评分为0、1、2和≥3的类别,初始病变成功率分别为97.0%、92.1%、86.5%和73.6%(p<0.001)。根据J-CTO评分为0、1、2和≥3的类别,一年时的TLR率分别为5.3%、11.1%、16.7%和13.4%(p=0.082)。根据J-CTO评分为0、1、2和≥3的类别,净中期成功率分别为91.9%、81.9%、72.1%和63.7%(p<0.001)。

结论

J-CTO评分较低的CTO病变患者有望获得较高的手术成功率和更高的无TLR生存率。J-CTO评分高的患者仍然是一个问题。

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