BA46的连通性参与语言的执行控制。
Connectivity of BA46 involvement in the executive control of language.
作者信息
Ardila Alfredo, Bernal Byron, Rosselli Monica
机构信息
Florida International University.
出版信息
Psicothema. 2016;28(1):26-31. doi: 10.7334/psicothema2015.174.
BACKGROUND
Understanding the functions of different brain areas has represented a major endeavor of contemporary neurosciences. Modern neuroimaging developments suggest cognitive functions are associated with networks rather than with specific areas.
OBJECTIVES
The purpose of this paper was to analyze the connectivity of Brodmann area (BA) 46 (anterior middle frontal gyrus) in relation to language.
METHODS
A meta-analysis was conducted to assess the language network in which BA46 is involved. The DataBase of Brainmap was used; 19 papers corresponding to 60 experimental conditions with a total of 245 subjects were included.
RESULTS
Our results suggest the core network of BA46. The localization and modules involved suggest BA46 participation in a “frontal language production system" (or extended Broca's system). The depicted BA46 connectivity is also concordant with a minor role in language semantics and language understanding.
CONCLUSION
It was concluded that BA46 plays a central role in the language production system, most likely related to its executive control.
背景
了解不同脑区的功能一直是当代神经科学的一项主要工作。现代神经影像学的发展表明，认知功能与网络相关，而非与特定脑区相关。
目的
本文旨在分析布罗德曼区（BA）46区（额中回前部）与语言相关的连接性。
方法
进行一项荟萃分析，以评估BA46区所参与的语言网络。使用了脑图谱数据库；纳入了19篇论文，对应60个实验条件，共245名受试者。
结果
我们的结果表明了BA46区的核心网络。所涉及的定位和模块表明BA46区参与了一个“额叶语言产生系统”（或扩展的布洛卡系统）。所描绘的BA46区连接性也与在语言语义和语言理解中起次要作用相一致。
结论
得出的结论是，BA46区在语言产生系统中起核心作用，很可能与其执行控制有关。
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