Weigel Angelika, König Hans-Helmut, Gumz Antje, Löwe Bernd, Brettschneider Christian
Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Hamburg- Eppendorf.
Department of Health Economics and Health Services Research, University Medical Center Hamburg- Eppendorf.
Int J Eat Disord. 2016 Jun;49(6):630-4. doi: 10.1002/eat.22512. Epub 2016 Feb 3.
We examined the association between disorder specific factors, comorbidity and health related quality of life (HRQoL) in anorexia nervosa (AN).
HRQoL was assessed using the EuroQol-5D visual analog scale (EQ-VAS) in this cross-sectional study. Three regression models were estimated to determine the association between AN subtype (restrictive vs. binge/purge), duration of the eating disorder (ED), age (adolescents vs. adults), ED pathology (EDE-Q), Body Mass Index (BMI), depressive symptoms (PHQ-9), somatic complaints (PHQ-15), anxiety (GAD-7) and EQ-VAS.
The sample comprised 218 female AN patients (mean age = 23.3 years [SD = 8.2]; mean EQ-VAS score = 53.4 [SD = 21.4]). A lower BMI, higher levels of depressive symptoms, and somatic complaints were significantly associated with lower EQ-VAS scores.
Findings of the present study suggest that BMI and comorbidity might be more relevant to HRQoL impairments in AN than age, diagnostic subtype, duration of the ED or current psychopathology. © 2016 Wiley Periodicals, Inc. (Int J Eat Disord 2016; 49:630-634).
我们研究了神经性厌食症(AN)中特定疾病因素、共病情况与健康相关生活质量(HRQoL)之间的关联。
在这项横断面研究中,使用欧洲五维健康量表视觉模拟评分(EQ-VAS)评估健康相关生活质量。估计了三个回归模型,以确定AN亚型(限制型与暴饮暴食/清除型)、饮食失调(ED)持续时间、年龄(青少年与成年人)、ED病理(饮食失调检查表-EQ)、体重指数(BMI)、抑郁症状(患者健康问卷-9)、躯体症状(患者健康问卷-15)、焦虑(广泛性焦虑障碍量表-7)与EQ-VAS之间的关联。
样本包括218名女性AN患者(平均年龄 = 23.3岁[标准差 = 8.2];平均EQ-VAS评分 = 53.4[标准差 = 21.4])。较低的BMI、较高水平的抑郁症状和躯体症状与较低的EQ-VAS评分显著相关。
本研究结果表明,在AN中,BMI和共病情况可能比年龄、诊断亚型、ED持续时间或当前精神病理学与HRQoL损害更相关。©2016威利期刊公司(《国际进食障碍杂志》2016年;49:630 - 634)。