Liu Yale, Li Tian, An Jingang, Zeng Weihui, Xiao Shengxiang
Department of Dermatology, The Second Affiliated Hospital, School of Medicine, Xi'an Jiaotong University, 157 Xiwu Road, Xincheng District, Xi'an, Shaanxi Province, 710004, People's Republic of China.
Department of Dermatology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, 710032, People's Republic of China.
Health Qual Life Outcomes. 2016 Feb 3;14:17. doi: 10.1186/s12955-016-0419-5.
The Dermatology Life Quality Index (DLQI) is the most widely used measure of health-related quality of life (HRQoL) associated with skin disease. Recently, the psychometric properties of the DLQI have caused some controversy because the instrument appears not to meet the requirements of modern test theory. The purpose of this study was to assess whether these psychometric issues also occur in Chinese patients with neurodermatitis.
One hundred fifty consecutive outpatients (83 males and 67 females) seeking treatment for neurodermatitis were assessed for eligibility for this prospective study between July 1, 2011 and September 30, 2011. The DLQI and a demographic questionnaire were completed. One female participant who incompletely answered the DLQI was excluded. Data were analyzed using the Rasch model in order to obtain meaningful scores for the DLQI. Scale assessment included analysis of rating scale function, item fit to the Rasch model, aspects of person-response validity, unidimensionality, person-separation reliability, and differential item function.
The rating scale advanced monotonically for all items in the DLQI, but item 9 did not demonstrate acceptable goodness-of-fit (Infit MnSq values >1.3) to the Rasch model. The 10 items of the DLQI met the criteria for person-separation reliability (PSI = 2.38) and the first latent dimension (general QoL) accounted for 50.8 % of the variance; but the variance explained by the second dimension (7.1 %) exceeded the criterion of 5 %. There were also limitations related to person-response validity, because ≥ 5 % (18.1 %) of cases demonstrated unacceptable fit. There was no uniform differential item functioning.
For neurodermatitis patients, the DLQI seems to have poor fit to the Rasch model; therefore, we recommend against using this instrument with neurodermatitis patients.
皮肤病生活质量指数(DLQI)是用于衡量与皮肤疾病相关的健康相关生活质量(HRQoL)的最广泛使用的指标。最近,DLQI的心理测量特性引发了一些争议,因为该工具似乎不符合现代测试理论的要求。本研究的目的是评估这些心理测量问题是否也出现在中国神经性皮炎患者中。
在2011年7月1日至2011年9月30日期间,对连续150名寻求神经性皮炎治疗的门诊患者(83名男性和67名女性)进行了本前瞻性研究的资格评估。完成了DLQI和一份人口统计学调查问卷。一名未完整回答DLQI的女性参与者被排除。使用Rasch模型分析数据,以便获得DLQI的有意义分数。量表评估包括对评分量表功能、项目与Rasch模型的拟合度、个人反应效度、单维度性、个人区分可靠性和项目差异功能等方面的分析。
DLQI中所有项目的评分量表均呈单调上升,但项目9对Rasch模型的拟合优度不可接受(拟合均方值>1.3)。DLQI的10个项目符合个人区分可靠性标准(PSI = 2.38),第一个潜在维度(总体生活质量)占方差的50.8%;但第二个维度解释的方差(7.1%)超过了5%的标准。在个人反应效度方面也存在局限性,因为≥5%(18.1%)的病例显示拟合不可接受。没有统一的项目差异功能。
对于神经性皮炎患者,DLQI似乎与Rasch模型的拟合度较差;因此,我们建议不要将该工具用于神经性皮炎患者。