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经尿道中段吊带植入术后10年随访:治愈率高,但膀胱过度活动症症状复发。

10 years follow-up after mid-urethral sling implantation: high rate of cure yet a re-occurrence of OAB-symptoms.

作者信息

Schauer Ingrid, Bock Helena, Eredics Klaus, Wallis Martina, Scholz Michael, Madersbacher Stephan, Lüftenegger Werner

机构信息

Department of Urology, Kaiser-Franz-Josef Hospital, Vienna, Austria.

出版信息

Neurourol Urodyn. 2017 Mar;36(3):614-619. doi: 10.1002/nau.22972. Epub 2016 Feb 9.

Abstract

AIMS

To assess the long-term outcome of mid-urethral slings regarding urinary incontinence (UI) and lower urinary tract symptoms and to identify risk factors for an unsatisfactory outcome.

METHODS

Analysis of a prospective institutional database. For the current analysis only women who reached the 10 years follow-up were eligible. Outcome was assessed using a detailed, non-validated questionnaire on continence status and on several aspects of lower urinary tract function.

RESULTS

A total of 256 women were operated during 1999-2004, in 139 (54.3%), a 10 years follow-up was available and these patients were included. Mean age at surgery was 63 years. At the 2, 5, and 10 years follow-up, the percentages of women reporting 0-1 pads/day were 96.4%, 97.1% and 88.5%, respectively. More than 95% of the patients reported no stress UI at the 2, 5, and 10 years follow-up. At baseline, urgency was reported by 61.2%, this figure dropped to 17.3% at 2 years and increased thereafter to 32.4% (5 years) and 41.7% (10 years). De novo urgency was present in 3.6% after 2 years, in 10.8% after 5 years, and 14.4% after 10 years. The percentage of patients with a high degree of treatment satisfaction declined from 79.1% at 2 years to 70.5% at 5 years, and 62.6% at 10 years. Risk factors for an unsatisfactory long-term outcome were advanced age, the presence of urgency, nocturia, and decreased bladder capacity at baseline.

CONCLUSIONS

This study confirms the excellent long-term efficacy of mid-urethral slings regarding the management of stress UI. A substantial number of women develop OAB-symptoms after the procedure that largely contribute to outcome dissatisfaction. Neurourol. Urodynam. 36:614-619, 2017. © 2016 Wiley Periodicals, Inc.

摘要

目的

评估中段尿道吊带术治疗尿失禁(UI)和下尿路症状的长期疗效,并确定治疗效果不佳的危险因素。

方法

对前瞻性机构数据库进行分析。本次分析仅纳入随访满10年的女性。使用一份详细的、未经验证的关于尿失禁状态和下尿路功能多个方面的问卷来评估治疗效果。

结果

1999年至2004年期间共有256名女性接受手术,其中139名(54.3%)有10年的随访数据并被纳入研究。手术时的平均年龄为63岁。在2年、5年和10年随访时,每天使用0 - 1片尿垫的女性比例分别为96.4%、97.1%和88.5%。超过95%的患者在2年、5年和10年随访时报告无压力性尿失禁。基线时,61.2%的患者有尿急症状,这一数字在2年时降至17.3%,此后在5年时升至32.4%,在10年时升至41.7%。术后2年新发尿急的患者占3.6%,5年时占10.8%,10年时占14.4%。治疗满意度高的患者比例从2年时的79.1%降至5年时的70.5%,10年时降至62.6%。长期治疗效果不佳的危险因素包括高龄、基线时存在尿急、夜尿症和膀胱容量减小。

结论

本研究证实中段尿道吊带术治疗压力性尿失禁具有良好的长期疗效。大量女性在手术后出现膀胱过度活动症症状,这在很大程度上导致了对治疗效果的不满意。《神经泌尿学与尿动力学》36:614 - 619,2017年。©2016威利期刊公司

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