Sodhi Surinder Pal Singh, Brar Ramandeep Singh, Singh Harkanwal Preet, Kaur Tajinder, Dhawan Rohan
Department of Oral Pathology and Microbiology, Dasmesh Institute of Research and Dental Sciences, Faridkot, Punjab, India.
J Cancer Res Ther. 2015 Oct-Dec;11(4):1023. doi: 10.4103/0973-1482.147391.
Basal cell adenoma (BCA) of the salivary glands is an uncommon type of monomorphic adenoma which constitutes 1% of all salivary gland tumors. It most commonly involves parotid gland, while it rarely occurs in minor salivary glands. Upper lip, buccal mucosa, and lower lip are the common intraoral sites; whereas, palate being the rarest one. Due to prognostic implications, differential diagnosis with basal cell adenocarcinoma, basaloid squamous cell carcinoma, and adenoid cystic carcinoma (AdCC) is mandatory. Considering the rarity of this lesion and histologic paradox regarding its diagnosis, we report a case of BCA of palate with emphasis on need of comprehensive immunohistochemical (IHC) analysis.
涎腺基底细胞腺瘤(BCA)是一种少见的单形性腺瘤,占所有涎腺肿瘤的1%。它最常累及腮腺,而在小涎腺中很少发生。上唇、颊黏膜和下唇是常见的口腔内发病部位;而腭部是最罕见的部位。由于其预后意义,必须与基底细胞腺癌、基底样鳞状细胞癌和腺样囊性癌(AdCC)进行鉴别诊断。鉴于该病变的罕见性及其诊断方面的组织学矛盾,我们报告一例腭部BCA病例,并强调全面免疫组织化学(IHC)分析的必要性。