Radeleff B, Sumkauskaite M, Kortes N, Gnutzmann D, Mokry T, Kauczor H U, Stampfl U
Sektion für Interventionelle Radiologie, Diagnostische und Interventionelle Radiologie, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Deutschland.
Radiologe. 2016 Mar;56(3):266-74. doi: 10.1007/s00117-016-0078-x.
CLINICAL/METHODICAL ISSUE: This article gives an overview of the current importance of so-called subintimal recanalization in the lower extremities.
The primary technical goal of endovascular interventions in the lower extremities is the endoluminal restoration of blood circulation from the iliac arteries into the feet.
If endoluminal recanalization of e.g. high-grade flow-relevant stenoses or chronic total occlusion (CTO) is technically not possible, subintimal recanalization is a promising option and the only remaining minimally invasive alternative. During subintimal recanalization a channel is intentionally generated in the vessel wall (dissection) in order to bypass e. g. a chronic vascular occlusion over as short a distance as possible.
The technical success rate for subintimal recanalization of CTO of the lower extremities is 65-100 %. Technical failure occurs in approximately 25 % using the catheter and wire technique and is caused in most cases by difficulties in reaching the true lumen after the subintimal passage (the so-called re-entry).
Compared to conventional subintimal recanalization, in recent years so-called re-entry devices have expanded the technical possibilities and depending on the medical experience and training level of the physician, provide an improvement in the technical success rate, a lower complication rate, a reduction of fluoroscopy time and the amount of necessary contrast medium but also result in higher costs.
Subintimal recanalization, whether carried out conventionally with a catheter and wire or using re-entry devices, of high-grade stenoses or CTO in the lower extremities provides a high technical success rate but requires an experienced and trained physician who is capable of operating the elaborate materials and mastering any possible complications.
临床/方法学问题:本文概述了所谓的下肢内膜下再通术目前的重要性。
下肢血管内介入治疗的主要技术目标是从髂动脉到足部实现腔内血液循环的恢复。
如果例如高度与血流相关的狭窄或慢性完全闭塞(CTO)的腔内再通在技术上不可行,内膜下再通是一个有前景的选择,也是唯一剩下的微创替代方法。在内膜下再通期间,有意在血管壁内形成一个通道(夹层),以便尽可能短距离地绕过例如慢性血管闭塞。
下肢CTO内膜下再通的技术成功率为65%-100%。使用导管和导丝技术时,技术失败率约为25%,大多数情况下是由于内膜下通过后进入真腔困难(所谓的再入)所致。
与传统的内膜下再通相比,近年来所谓的再入装置扩大了技术可能性,根据医生的医学经验和培训水平,提高了技术成功率,降低了并发症发生率,减少了透视时间和所需造影剂的用量,但也导致成本更高。
下肢高度狭窄或CTO的内膜下再通,无论是传统地使用导管和导丝进行,还是使用再入装置进行,都具有较高的技术成功率,但需要一位经验丰富且经过培训的医生,其能够操作精密的材料并掌握任何可能出现的并发症。