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胆总管结石所致急性胆管炎患者内镜下胆道支架置入术与鼻胆管引流术的比较:内镜下胆道支架置入术有用吗?

Comparison Between Endoscopic Biliary Stenting and Nasobiliary Drainage in Patients with Acute Cholangitis due to Choledocholithiasis: Is Endoscopic Biliary Stenting Useful?

作者信息

Otani Keisuke, Ueki Toshiharu, Matsumura Keiichiro, Maruo Toru, Minoda Ryohei, Otsuka Yuichiro, Kawamoto Kenichiro, Noma Ejiro, Mitsuyasu Tomoko, Matsui Toshiyuki

出版信息

Hepatogastroenterology. 2015 May;62(139):558-63.

Abstract

BACKGROUND/AIMS: To clarify whether or not use of an endoscopic biliary stenting (EBS) is superior to endoscopic nasobiliary drainage (ENBD) in cases of acute cholangitis due to choledocholithiasis.

METHODOLOGY

Of 447 patients with choledocholithiasis who were treated in the Department of Gastroenterology, Fukuoka University Chikushi Hospital between January 1994 and September 2006, the subjects were 99 moderate acute cholangitis patients who underwent endoscopic drainage as initial treatment. Clinical efficacy, complications and patient satisfaction (meal intake rete) were investigated in the EBS group (67 patients) and the ENBD group (32 patients).

RESULTS

There were no significant differences in the improvement in inflammation, total bilirubin, or biliary enzymes between the EBS and ENBD groups. Catheter occlusion was seen in three patients (4%) in the EBS group, and the catheter was self-extracted by three patients (10%) in the ENBD group.

CONCLUSION

In moderate acute cholangitis due to choledocholithisis, the treatment efficacy and safety of EBS are equal to those of ENBD, and EBS appears to be a better choice in elderly patients in particular.

摘要

背景/目的:明确在胆总管结石所致急性胆管炎病例中,内镜下胆道支架置入术(EBS)是否优于内镜下鼻胆管引流术(ENBD)。

方法

1994年1月至2006年9月间,在福冈大学筑紫医院胃肠病科接受治疗的447例胆总管结石患者中,选取99例接受内镜引流作为初始治疗的中度急性胆管炎患者作为研究对象。对EBS组(67例患者)和ENBD组(32例患者)的临床疗效、并发症及患者满意度(进食率)进行了调查。

结果

EBS组和ENBD组在炎症改善、总胆红素或胆汁酶方面无显著差异。EBS组有3例患者(4%)出现导管堵塞,ENBD组有3例患者(10%)自行拔除了导管。

结论

在胆总管结石所致中度急性胆管炎中,EBS的治疗效果和安全性与ENBD相当,尤其对于老年患者,EBS似乎是更好的选择。

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